Treatment of basal cell carcinoma of the skin with curettage

Reymann, F.

doi:10.1001/archderm.103.6.623

Cited by 9 publications

(5 citation statements)

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“…This retrospective study included 345 IECs treated with curettage (treatment protocol not specified), an overall clearance rate of 81% (65 recurrences) was reported with 35% of the patients followed up for <1 year, 30% for 1–4 years and 35% for >5 years 14 . Curettage has also proven to be effective for BCC and SCC 18,19 . Our research group recently published results from a randomized controlled trial showing 1‐year overall clearance rates of 95.7% with curettage for superficial BCCs compared to 100% with cryosurgery 20 .…”

Section: Discussionmentioning

confidence: 99%

“…14 Curettage has also proven to be effective for BCC and SCC. 18,19 Our research group recently published results from a randomized controlled trial showing 1-year overall clearance rates of 95.7% with curettage for superficial BCCs compared to 100% with cryosurgery. 20 Barlow et al 21 retrospectively evaluated curettage for non-aggressive BCCs reporting a 96.0% 5-year clearance rate.…”

Section: Discussionmentioning

confidence: 99%

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Cryosurgery versus curettage for intraepidermal carcinoma: A randomized controlled trial

Fougelberg,

Backman,

Hasselquist

et al. 2023

Acad Dermatol Venereol

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BackgroundCryosurgery is a common destructive treatment method for intraepidermal carcinoma (IEC) above the knee. Curettage alone is a simple, non‐aggressive and inexpensive treatment method commonly used on benign skin lesions. However, only one study has assessed curettage for treatment of IEC.ObjectiveWe aimed to (1) compare the effectiveness of cryosurgery (standard method) to curettage (experimental method) for treatment of IEC in regard to overall clearance rates at 1‐year follow‐up, and (2) investigate whether wound healing times differed between the treatment groups.MethodsIn this randomized and controlled, non‐inferiority trial, adult patients with one or more IEC with a diameter of 5–20 mm, located above the knee and suitable for destructive treatment were recruited from Sahlgrenska University Hospital (Gothenburg, Sweden). Lesions were randomized to treatment with either cryosurgery or curettage. Wound healing was assessed by a nurse after 4–6 weeks and through self‐report forms. Overall clearance was assessed by a dermatologist after 1 year.ResultsIn total, 183 lesions in 147 patients were included, with 93 lesions randomized to cryosurgery and 90 to curettage. Eighty‐eight (94.6%) of the lesions in the cryosurgery group and 71 (78.9%) in the curettage group showed an overall clearance at the 1‐year follow‐up visit (p = 0.002). The non‐inferiority analysis was inconclusive. Curettage resulted in both shorter self‐reported wound healing times (mean time 3.1 vs. 4.8 weeks, p < 0.001) and a larger proportion of healed wounds after 4–6 weeks (p < 0.001).ConclusionsCryosurgery and curettage both result in high clearance rates for treatment of IEC, but cryosurgery is significantly more effective. On the other hand, curettage may result in shorter wound healing times.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cryosurgery versus curettage for intraepidermal carcinoma: A randomized controlled trial

Fougelberg,

Backman,

Hasselquist

et al. 2023

Acad Dermatol Venereol

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“…Originally, the series was comprised of 178 patients with a total of 338 basal cell carcinomas, treated over the period ex¬ tending from April 1,1968 to April 1,1970. The collection of the series, and the distribution according to sex and age were described in the previous paper …”

Section: Methodsmentioning

confidence: 99%

Treatment of basal cell carcinoma of the skin with curettage. II. A follow-up study

Reymann¹

1973

Archives of Dermatology

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“…The results have been described in two papers [8,9], and a survey from 1977 [10] shows that the recurrence rate, with curettage as sole treatment of basal cell carcinoma, is less than 5 as regards the multiple tumours; this may be due to the fact that the number of super ficial carcinomas is rather large in this group. As regards solitary basal cell carcinomas, the recurrence rate is 10% or slightly higher, depending on site, duration, etc., of the tumour.…”

Section: Commentsmentioning

confidence: 99%

Treatment of Basal Cell Carcinoma of the Skin with 5-Fluorouracil Ointment

Reymann¹

1979

Dermatology

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During the period 1966–1968, 88 patients with a total of 95 basal cell carcinomas were treated with 5% 5-fluorouracil ointment. A follow-up study carried out from November 1977 to January 1978 revealed a total of 12 recurrences in 56 surviving patients with 56 basal cell carcinomas. The recurrence rate is thus 21.4%. It is concluded that there is hardly any indication for using 5-fluorouracil in local treatment of nodular basal cell carcinoma.

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Treatment of basal cell carcinoma of the skin with curettage

Cited by 9 publications

References 0 publications

Cryosurgery versus curettage for intraepidermal carcinoma: A randomized controlled trial

Cryosurgery versus curettage for intraepidermal carcinoma: A randomized controlled trial

Treatment of basal cell carcinoma of the skin with curettage. II. A follow-up study

Treatment of Basal Cell Carcinoma of the Skin with 5-Fluorouracil Ointment

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