Treatment of Anogenital Warts by Pulsed Dye Laser

Tuncel, Asuman; Görğü, Metin; Ayhan, Meltem; Deren, Orgun; Erdoğan, Bülent

doi:10.1046/j.1524-4725.2002.01172.x

Cited by 21 publications

(19 citation statements)

References 12 publications

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“…The clearance rate varied according to site, with 99% for genitalia [9], which is similar to our results for the FPDL treatment. Tuncel et al reported a complete healing of extensive perianal warts in a healthy 3-year-old boy after one FPDL treatment [11].…”

Section: Discussionmentioning

confidence: 99%

Pulsed dye laser treatment of genital warts

2006

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Section: Discussionmentioning

confidence: 99%

Pulsed dye laser treatment of genital warts

2006

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“…114 It produces less pain and scarring than with CO2 laser treatment and has been used for facial warts and perianal warts in children. 20,138,139 Pulse dye laser has been reported to result in complete remission in 48% to 95% of cases. 102,137,[140][141][142][143][144][145][146][147] One study found no statistically significant difference among cure rates between pulsed dye laser (66%) compared to conventional cryotherapy or cantharidin therapy (70%).…”

Section: Neodymium:yag (Nd:yag) Lasermentioning

confidence: 99%

An Armamentarium of Wart Treatments

Lipke¹

2006

Clinical Medicine & Research

282

295

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Patients and clinicians experience the frustration of cutaneous viral warts caused by infection with the human papilloma virus (HPV).Warts appear in various forms on different sites of the body and include common warts (verruca vulgaris), plane or flat warts, myrmecia, plantar warts, coalesced mosaic warts, filiform warts, periungual warts, anogenital warts (venereal or condyloma acuminata), oral warts and respiratory papillomas. Cervical infection with HPV is now known to cause cervical cancer if untreated. A review of the medical literature reveals a huge armamentarium of wart monotherapies and combination therapies. Official evidence-based guidelines exist for the treatment of warts, but very few of the reported treatments have been tested by rigorous blinded, randomized controlled trials.Therefore, official recommendations do not often include treatments with reportedly high success rates, but they should not be ignored when considering treatment options. It is the purpose of this review to provide a comprehensive overview of the wart treatment literature to expand awareness of the options available to practitioners faced with patients presenting with problematic warts. Warts of the genital tract carry a much more ominous and pernicious threat for women in particular. It has been estimated that up to 70% of sexually active women become infected during their lifetime with human papillomavirus (HPV), the infective agent that causes warts. 3-5 A causal role for HPV infections in cervical cancer has been documented beyond reasonable doubt. HPV DNA is present in virtually all cervical cancer cases worldwide, with it being detected in 99.7% of an international series of cervical cancers by genetic amplification techniques and in 100% of cases as confirmed by histological review. 6,7 Cervical cancer is the most frequent common cancer in developing countries and the second most common cancer in women worldwide. 3 The association between HPV infection and cervical cancer is so strong that HPV is now considered the first positive cause of any human cancer ever identified. 3This raises the level of concerns over HPV prevention, screening and treatment from that of a nuisance condition to that of a major public health concern. Attention is beginning to focus on the viral factors that determine persistence and neoplastic progression to cancer and the possible role of HPV in other nongenital cancers (e.g., skin, upper aerodigestive tract). [8][9][10][11][12][13][14][15][16][17] Patients with warts seek advice from general practitioners, pharmacists, naturopaths, allied health professionals, family or friends, dermatologists, gynecologists, obstetricians and pediatricians for treatment and may present with recalcitrant warts that have been previously treated with anything from folk remedies to hypnosis to over-the-counter medications to more aggressive clinic-based treatments. Unfortunately, even with years of medical literature on this subject, high-quality, level I evidence for the efficacy of almost all treatments is no...

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“…30 In children, there has been 1 case report of using a pulsed-dye laser in a 3-year-old to clear treatmentresistant perianal warts; however, more studies are needed to determine the safety and efficacy of lasers in children. 31 …”

Section: Physical Destructionmentioning

confidence: 99%