Treatment of a nonresponding port-wine stain with a new pulsed light source (PhotoDerm® VL)

Raulin, Christian; Hellwig, S.; Schönermark, Matthias P.

doi:10.1002/(sici)1096-9101(1997)21:2<203::aid-lsm13>3.0.co;2-f

Cited by 62 publications

(36 citation statements)

References 17 publications

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“…Die Pausen zwischen den entsprechenden Impulssequenzen sind ebenfalls variabel von 10-500 ms wählbar. Diese Verzögerung ermöglicht eine Abkühlung der Epidermis und der kleinen Gefäße zwischen den einzelnen Impulsen, während sich die tiefer gelegenen, größeren Gefäße Das PhotoDerm®VL ist eine hochenergetische Blitzlampe, die polychromatisches Licht aussendet und zur Behandlung sowohl gutartiger vaskulärer Malformationen unterschiedlicher Tiefe und Ausdehnung (kavernöse Häman-giome, benigne venöse Malformationen, Naevi flammei, essentiellen Teleangiektasien, Besenreiservarikosis, Erythrosis interfollicularis colli) als auch kosmetisch störender Hypertrichose geeignet ist [8,9,[18][19][20][21].…”

Section: Einsatzgebiete Einer Hochenergetischen Blitzlampe (Photodermunclassified

“…den, daß die oberflächlichen (bis 300 µm) und eher größeren Gefäße (38 µm) besser auf eine Farbstofflasertherapie ansprechen als tieferliegende mit kleinem (20 µm) Durchmesser [6]. In diesen Fällen konnten mit dem PhotoDerm®VL gute bis sehr gute Resultate erzielt werden [17,19]. Andere Autoren hingegen berichten über ein besseres Ansprechen auf den gepulsten Farbstofflaser vs. PhotoDerm®VL unter Verwendung jeweils konstanter Behandlungsparameter (570 nm-1200 nm, 40 J/cm 2 , 5 ms im Einfachimpuls) bei mög-licherweise unterschiedlicher Ausgangssituation bezüglich Farbintensität, Tiefe und Durchmesser der Gefä-ße [29].…”

Section: Essentielle Teleangiektasienunclassified

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Einsatzgebiete einer hochenergetischen Blitzlampe (PhotoDerm®VL)

1997

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By varying the light spectrum, impulse length, impulse sequences and fluences, the PhotoDerm VL allows a large choice of individual treatment parameters. Superficial as well as deeper localized vascular malformations (essential telangiectases, port-wine stains, Poikiloderma of Civatte, hemangiomatous malformations) and cosmetically bothering hypertrichosis can be treated successfully with this high intensity polychromatic pulsed light source.

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Section: Einsatzgebiete Einer Hochenergetischen Blitzlampe (Photodermunclassified

Section: Essentielle Teleangiektasienunclassified

Einsatzgebiete einer hochenergetischen Blitzlampe (PhotoDerm®VL)

1997

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“…In this technique, laser absorption on the surface sample can be monitored remotely using an infrared (IR) sensor. Recently, the PRT has been used to study the skin under various circumstances, for example, (a) in skin pathologies [10], (b) in the study of over-heating damage in laser surgery [11], (c) in the case of topical skin penetration, and (d) in skin hydration [12]. The PRT can be used in either the frequency (sinusoidal modulation excitation) or the time domain (pulsed excitation).…”

Section: Introductionmentioning

confidence: 99%

“…The photothermal radiometry technique in the time domain (PRTT) has been applied to the evaluation of the thickness of surface coatings in industrial components, identification of sub-surface features, such as micro-cracks in aircraft structures, the determination of the optical absorption coefficient in human arteries, and the characterization of vascular lesions and monitoring of laser damage during surgery [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

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Study of Skin Phantoms by Photothermal Radiometry in Frequency Domain and Multivariate Methods

et al. 2008

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In this paper the use of the photothermal radiometry technique in the frequency domain (PRTF) and the use of multivariate methods in the study of two types of skin phantoms: (a) one in which skin pigmentation was simulated dyeing the gel phantom and (b) the other consists of exposure of animal skin samples to different degrees of thermal damage. In experiment (a), gel phantoms were prepared with different concentrations of methylene blue (MB). The mean values of the radiometry signal (RS) show significant differences in only those cases in which changes in the concentration of MB were higher than 0.38 mM. This result was confirmed with a t test for independent samples of the data ( p < 0.05). The mean values of the amplitude and phase signal do not permit discrimination between phantoms with changes in pigmentation equal to or lower than this value. However, principal component analysis (PCA) demonstrated that it is possible to discriminate between phantoms with changes in molar concentration equal to 0.38 mM (for the phase signal). In the case of experiment (b), the following four groups of pork skin samples were analyzed: one consists of samples of fresh skin, while the other three consist of samples exposed to thermal damage at 45 • C (the exposure time was 4 s) and 80 • C (exposure times were 4 s and 8 s, respectively). The mean values of the RS for each group of samples did not show a clear visual discrimination. However, the t test for independent samples applied to the data demonstrated significant differences only between fresh skin and skin exposure to thermal damage at 80 • C (with exposure times of 4 s and 8 s). PCA was used to discriminate between the four different skin samples.

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Treatment of Port-wine Stains With a Noncoherent Pulsed Light Source

Raulin¹,

Schroeter²,

Weiß³

et al. 1999

Arch Dermatol

129

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Objective: The flashlamp pulsed dye laser (FLPDL) is currently the treatment of choice for port-wine stains (PWS). We recently investigated whether a non-coherent intense pulsed light source (IPLS) would be effective in the therapy of PWS. Design and Patients:In order to evaluate the efficacy in treatment of PWS (especially adult-type dark and hypertrophic), a retrospective study of 37 patients (randomly selected) with a total of 40 PWS treated with IPLS was initiated. Clinical PWS characteristics recorded were color and location of the PWS. Data collected included treatment parameters (filters, pulse duration, fluence and pulse sequencing), % clearance, and side effects (purpura, blisters, crusting, altered pigmentation and scarring).Results: Good and complete (70-100 %) clearance was achieved in 28 of 40 PWS treated with IPLS. Average number of treatment sessions in PWS reaching 100 % clearance included 4.0 for pink PWS and 1.5 sessions for red PWS. Average number of sessions in purple PWS reaching good clearance (70-99%) was 4.2 sessions. Parameters used most frequently were 515 and 550 nm cut-off-filters, pulse duration of 2.5-5.0 ms and fluences of 24 to 60 J/cm 2 . Side effects included purpura in 76%, superficial blisters in 8% and crusting in 20%. Transient pigmentation changes were seen in 10.8% of patients (hypopigmentations in 8.1%, hyperpigmentation in 2.7%). No scarring was observed. Conclusion:IPLS presents an effective and safe method for treating PWS, especially dark and facial PWS.

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Treatment of a nonresponding port-wine stain with a new pulsed light source (PhotoDerm® VL)

Cited by 62 publications

References 17 publications

Einsatzgebiete einer hochenergetischen Blitzlampe (PhotoDerm®VL)

Einsatzgebiete einer hochenergetischen Blitzlampe (PhotoDerm®VL)

Study of Skin Phantoms by Photothermal Radiometry in Frequency Domain and Multivariate Methods

Treatment of Port-wine Stains With a Noncoherent Pulsed Light Source

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