Trapping of Au nanoparticles in a microfluidic device using dielectrophoresis for surface enhanced Raman spectroscopy

Almeida, Gabriela Brito; Poppi, Ronei J.; Silva, José Alberto Fracassi da

doi:10.1039/c6an01497f

Cited by 13 publications

(7 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The device was reported to trap β‐galactosidase due to nDEP under an applied electric potential difference of 100 V DC and IgG due to nDEP under an applied electric potential difference of 50 V DC. Another work trapped 80 nm gold nanoparticles in 200 μm circular posts with a 50 μm gap between posts in an 8‐column array at voltages ranging from 240 to 360 V [88]. Two years later, another study [89] used a 100 V pp AC signal at frequencies ranging from 0.1 to 20 MHz to manipulate human embryonic kidney cells.…”

Section: Voltage Reduction Strategies In Insulator‐based Devicesmentioning

confidence: 99%

Toward low‐voltage dielectrophoresis‐based microfluidic systems: A review

2020

View full text Add to dashboard Cite

Dielectrophoretically driven microfluidic devices have demonstrated great applicability in biomedical engineering, diagnostic medicine, and biological research. One of the potential fields of application for this technology is in point‐of‐care (POC) devices, ideally allowing for portable, fully integrated, easy to use, low‐cost diagnostic platforms. Two main approaches exist to induce dielectrophoresis (DEP) on suspended particles, that is, electrode‐based DEP and insulator‐based DEP, each featuring different advantages and disadvantages. However, a shared concern lies in the input voltage used to generate the electric field necessary for DEP to take place. Therefore, input voltage can determine portability of a microfluidic device. This review outlines the recent advances in reducing stimulation voltage requirements in DEP‐driven microfluidics.

show abstract

Section: Voltage Reduction Strategies In Insulator‐based Devicesmentioning

confidence: 99%

Toward low‐voltage dielectrophoresis‐based microfluidic systems: A review

2020

View full text Add to dashboard Cite

show abstract

“…Nanoparticles are bulk materials that are three dimensional at the nanometer scale. In recent years, nanoparticles have been widely implemented for nanoscience applications . Thus, effective and efficient nanoparticle manipulation are significant for advancement in these fields.…”

Section: Dielectrophoretic Manipulation Of Nanomaterialsmentioning

confidence: 99%

Dielectrophoretic manipulation of nanomaterials: A review

et al. 2018

View full text Add to dashboard Cite

Nanomaterials manipulation using dielectrophoresis (DEP) is one of the major research areas that could potentially benefit the micro/nano science for diverse applications, such as microfluidics, nanomachine, and biosensor. The innovation and development of basic theories, methods or applications will have a huge impact on the entire related field. Specifically, for DEP manipulation of nanomaterials, improvements in comprehensive performance of accuracy, flexibility and scale could promote broader applications in micro/nano science. Therefore, to explore the directions for future research, this paper critically provides an overview on the fundamentals, recent progress, current challenges, and potential applications of DEP manipulation of nanomaterials. This review will also act as a guide and reference for researchers to explore promising applications in relevant research.

show abstract

“…This technique was further extended for detecting adenine . Microfluidic-based DEP has also been used to trap bacteria with subsequent chemical analysis and identification using SERS. − More recently, an insulator-dielectrophoresis-based microfluidic device has been reported for detection of crystal violet using SERS . In the current study, we report the use of a DEP-SERS platform as a reusable probe for detecting drugs of abuse in saliva.…”

mentioning

confidence: 90%

“…25−27 More recently, an insulator-dielectrophoresis-based microfluidic device has been reported for detection of crystal violet using SERS. 28 In the current study, we report the use of a DEP-SERS platform as a reusable probe for detecting drugs of abuse in saliva.…”

mentioning

confidence: 99%

Dielectrophoretic Nanoparticle Aggregation for On-Demand Surface Enhanced Raman Spectroscopy Analysis

et al. 2018

View full text Add to dashboard Cite

Rapid chemical identification of drugs of abuse in biological fluids such as saliva is of growing interest in healthcare and law enforcement. Accordingly, a label-free detection platform that accepts biological fluid samples is of great practical value. We report a microfluidics-based dielectrophoresis-induced surface enhanced Raman spectroscopy (SERS) device, which is capable of detecting physiologically relevant concentrations of methamphetamine in saliva in under 2 min. In this device, iodide-modified silver nanoparticles are trapped and released on-demand using electrodes integrated in a microfluidic channel. Principal component analysis (PCA) is used to reliably distinguish methamphetamine-positive samples from the negative control samples. Passivation of the electrodes and flow channels minimizes microchannel fouling by nanoparticles, which allows the device to be cleared and reused multiple times.

show abstract

Trapping of Au nanoparticles in a microfluidic device using dielectrophoresis for surface enhanced Raman spectroscopy

Cited by 13 publications

References 23 publications

Toward low‐voltage dielectrophoresis‐based microfluidic systems: A review

Toward low‐voltage dielectrophoresis‐based microfluidic systems: A review

Dielectrophoretic manipulation of nanomaterials: A review

Dielectrophoretic Nanoparticle Aggregation for On-Demand Surface Enhanced Raman Spectroscopy Analysis

Contact Info

Product

Resources

About