This paper describes particle transport in Stokes flow in a two-dimensional corner whose walls oscillate, which is a simple model for particle transport in the pulmonary alveoli. Formally speaking, the wall motion produces a perturbation to the wellknown Moffatt corner eddies. However, this 'perturbation' is dominant as the corner is approached. The motion of particles is regular near to the corner. Far from the corner, chaotic motion within the main part of the flow is restricted to very small regions. We deduce that there is competition between the far-field motion that generates eddies and the wall motion. The relative strengths of these two motions determines whether a given particle moves regularly or chaotically. Consequently, there is an intermediate region in which chaotic transport is maximized.
IntroductionThis mathematical study is motivated by an ongoing investigation into particle motion in the lung, led by Tsuda, that combines physiological, mathematical and computational studies of chaos in alveoli. These are cavities in the lower airway walls in which recirculation can occur. Tsuda, Henry & Butler (1995) examined the effects of cyclic expansion and contraction of alveolar walls on fluid flow in such a cavity by developing a numerical model. It was observed that low-Reynolds-number alveolar flow can be extremely complex; it was presumed that the alveolated duct structure and its time-dependent motion induced this complexity. In a related study, Haber et al. (2000) developed an analytical model of a cyclically expanding and contracting spherical alveolus and its vicinity. Their results supported the observation that there is a level of complexity of particle mixing in this region of the lungs. Moreover, the geometric features of structural alveolation and rhythmic expansion were given as the mechanism for chaotic mixing of particles. The numerical simulations of Henry, quantified the effects of cyclic expansion and contraction of an alveolated duct upon particle motion in the model alveoli. Lagrangian tracking of fluid particles indicated that the trajectories exhibit unpredictable stretched and folded patterns. These observations led Tsuda et al. (2002) to hypothesize that chaotic flow can occur in alveolated airways, and that this can result in flow-induced aerosol mixing and deposition deep in the lung. Tsuda's group tested this hypothesis by performing flow visualization experiments in excised animal lungs. They ventilated lungs with ultra-low-viscosity, polymerizable, Newtonian fluids of two colours. Each lung was first filled with white fluid, then ventilated with blue fluid for a number of cycles, ensuring that the Reynolds number remained low throughout the experiment. Then ventilation was halted and the fluids were polymerized to make casts that showed the final position of fluid particles. Recirculation had occurred in many alveoli, and there was substantial mixing of the fluids after just two cycles of inspiration and expiration.