Transplantation for liver and biliary cancer

Salvage Liver Transplantation Is a Reasonable Option for Selected Patients Who Have Recurrent Hepatocellular Carcinoma after Liver Resection

“…However, the donor organ shortage has been a major worldwide limitation to the use of PLT for small resectable HCC [17], [18]. The long-term waiting lists due to this donor shortage may result in tumor progression, which in turn leads to potential drop-out from the waiting list [19].…”

Salvage Liver Transplantation Is a Reasonable Option for Selected Patients Who Have Recurrent Hepatocellular Carcinoma after Liver Resection

“…However, the donor organ shortage has been a major worldwide limitation to the use of PLT for small resectable HCC [17], [18]. The long-term waiting lists due to this donor shortage may result in tumor progression, which in turn leads to potential drop-out from the waiting list [19].…”

Resection of hepatocellular carcinoma in patients without cirrhosis

“…Currently liver transplantation is not the treatment of choice for HCC in patients without cirrhosis. Indeed, survival after transplantation is similar to that after resection, and recurrence rates are unacceptably high23. Patient selection has probably affected outcome significantly to date, as did the pre‐Milan criteria for transplantation.…”

Beyond Milan criteria – chances and risks of expanding transplantation criteria for HCC patients with liver cirrhosis

“…However, in more than 80% of patients, HCC is associated with liver cirrhosis at different stages. Therefore, only 10-15% of HCC patients are potentially resectable, opening this option only to a minority of patients (89). Furthermore, advanced age and progression on listing were the major causes of exclusion from final liver replacement.…”

Salvage Liver Transplantation Is a Reasonable Option for Selected Patients Who Have Recurrent Hepatocellular Carcinoma after Liver Resection

“…However, the donor organ shortage has been a major worldwide limitation to the use of PLT for small resectable HCC [17], [18]. The long-term waiting lists due to this donor shortage may result in tumor progression, which in turn leads to potential drop-out from the waiting list [19].…”

Resection of hepatocellular carcinoma in patients without cirrhosis

“…Currently liver transplantation is not the treatment of choice for HCC in patients without cirrhosis. Indeed, survival after transplantation is similar to that after resection, and recurrence rates are unacceptably high23. Patient selection has probably affected outcome significantly to date, as did the pre‐Milan criteria for transplantation.…”

Beyond Milan criteria – chances and risks of expanding transplantation criteria for HCC patients with liver cirrhosis

“…However, in more than 80% of patients, HCC is associated with liver cirrhosis at different stages. Therefore, only 10-15% of HCC patients are potentially resectable, opening this option only to a minority of patients (89). Furthermore, advanced age and progression on listing were the major causes of exclusion from final liver replacement.…”

Salvage Liver Transplantation Is a Reasonable Option for Selected Patients Who Have Recurrent Hepatocellular Carcinoma after Liver Resection

“…However, the donor organ shortage has been a major worldwide limitation to the use of PLT for small resectable HCC [17], [18]. The long-term waiting lists due to this donor shortage may result in tumor progression, which in turn leads to potential drop-out from the waiting list [19].…”

Resection of hepatocellular carcinoma in patients without cirrhosis

“…Currently liver transplantation is not the treatment of choice for HCC in patients without cirrhosis. Indeed, survival after transplantation is similar to that after resection, and recurrence rates are unacceptably high23. Patient selection has probably affected outcome significantly to date, as did the pre‐Milan criteria for transplantation.…”

Beyond Milan criteria – chances and risks of expanding transplantation criteria for HCC patients with liver cirrhosis

“…However, in more than 80% of patients, HCC is associated with liver cirrhosis at different stages. Therefore, only 10-15% of HCC patients are potentially resectable, opening this option only to a minority of patients (89). Furthermore, advanced age and progression on listing were the major causes of exclusion from final liver replacement.…”