Transplacental versus direct fetal corticosteroid treatment for accelerating fetal lung maturation where there is a risk of preterm birth

The Clinical Usefulness of Predictive Models for Preterm Birth with Potential Benefits: A KOrean Preterm collaboratE Network (KOPEN) Registry-Linked Data-Based Cohort Study

“…Accurate estimation of preterm birth risk using prediction models improves patient satisfaction after preterm management. In particular, a small change in gestational time by delaying labor could significantly reduce neonatal morbidity and mortality by allowing for an intervention period to accelerate fetal lung maturation [29].…”

The Clinical Usefulness of Predictive Models for Preterm Birth with Potential Benefits: A KOrean Preterm collaboratE Network (KOPEN) Registry-Linked Data-Based Cohort Study

“…Accurate estimation of preterm birth risk using prediction models improves patient satisfaction after preterm management. In particular, a small change in gestational time by delaying labor could significantly reduce neonatal morbidity and mortality by allowing for an intervention period to accelerate fetal lung maturation [29].…”

Effectiveness of an oral versus sublingual loading dose of nifedipine for tocolysis

“…Nevertheless, when the frequency of tocolysis in 12 hours and in 48 hours was analyzed, as well as the frequency of premature delivery in the first 48 hours, there was no difference between sublingual and oral nifedipine, suggesting that when therapeutic plasma levels are reached the drug is effective in inhibiting premature delivery regardless of the route of administration . This interval of 48 hours is particularly important because it permits corticosteroid administration to accelerate fetal lung maturation, which appears to be one of the principal functions of tocolytic therapy given the numerous beneficial effects resulting from its administration …”

The Effect of Antenatal Corticosteroid Therapy to Respiratory Distress Syndrome Event on Preterm Infants in Surabaya

“…In addition, there was no evidence of negative effects of corticosteroids in the mother and infants longterm goals in both. [5][6][7][8] Liggins and Howie conducted a randomized study of 12 mg intra-muscular betamethasone, 2 times within 24 hours, resulting in a significant reduction in the incidence of Respiratory Distress Syndrome (RDS) and a decrease in perinatal mortality born before 34 weeks. The treatment of betamethasone antenatal reduced the incidence of RDS ± 30% from 15.6% to 10% (P = 0.02) to 853 infants.…”

The Clinical Usefulness of Predictive Models for Preterm Birth with Potential Benefits: A KOrean Preterm collaboratE Network (KOPEN) Registry-Linked Data-Based Cohort Study

“…Accurate estimation of preterm birth risk using prediction models improves patient satisfaction after preterm management. In particular, a small change in gestational time by delaying labor could significantly reduce neonatal morbidity and mortality by allowing for an intervention period to accelerate fetal lung maturation [29].…”

Effectiveness of an oral versus sublingual loading dose of nifedipine for tocolysis

“…Nevertheless, when the frequency of tocolysis in 12 hours and in 48 hours was analyzed, as well as the frequency of premature delivery in the first 48 hours, there was no difference between sublingual and oral nifedipine, suggesting that when therapeutic plasma levels are reached the drug is effective in inhibiting premature delivery regardless of the route of administration . This interval of 48 hours is particularly important because it permits corticosteroid administration to accelerate fetal lung maturation, which appears to be one of the principal functions of tocolytic therapy given the numerous beneficial effects resulting from its administration …”

The Effect of Antenatal Corticosteroid Therapy to Respiratory Distress Syndrome Event on Preterm Infants in Surabaya

“…In addition, there was no evidence of negative effects of corticosteroids in the mother and infants longterm goals in both. [5][6][7][8] Liggins and Howie conducted a randomized study of 12 mg intra-muscular betamethasone, 2 times within 24 hours, resulting in a significant reduction in the incidence of Respiratory Distress Syndrome (RDS) and a decrease in perinatal mortality born before 34 weeks. The treatment of betamethasone antenatal reduced the incidence of RDS ± 30% from 15.6% to 10% (P = 0.02) to 853 infants.…”

The Clinical Usefulness of Predictive Models for Preterm Birth with Potential Benefits: A KOrean Preterm collaboratE Network (KOPEN) Registry-Linked Data-Based Cohort Study

“…Accurate estimation of preterm birth risk using prediction models improves patient satisfaction after preterm management. In particular, a small change in gestational time by delaying labor could significantly reduce neonatal morbidity and mortality by allowing for an intervention period to accelerate fetal lung maturation [29].…”

Effectiveness of an oral versus sublingual loading dose of nifedipine for tocolysis

“…Nevertheless, when the frequency of tocolysis in 12 hours and in 48 hours was analyzed, as well as the frequency of premature delivery in the first 48 hours, there was no difference between sublingual and oral nifedipine, suggesting that when therapeutic plasma levels are reached the drug is effective in inhibiting premature delivery regardless of the route of administration . This interval of 48 hours is particularly important because it permits corticosteroid administration to accelerate fetal lung maturation, which appears to be one of the principal functions of tocolytic therapy given the numerous beneficial effects resulting from its administration …”

The Effect of Antenatal Corticosteroid Therapy to Respiratory Distress Syndrome Event on Preterm Infants in Surabaya

“…In addition, there was no evidence of negative effects of corticosteroids in the mother and infants longterm goals in both. [5][6][7][8] Liggins and Howie conducted a randomized study of 12 mg intra-muscular betamethasone, 2 times within 24 hours, resulting in a significant reduction in the incidence of Respiratory Distress Syndrome (RDS) and a decrease in perinatal mortality born before 34 weeks. The treatment of betamethasone antenatal reduced the incidence of RDS ± 30% from 15.6% to 10% (P = 0.02) to 853 infants.…”