2015
DOI: 10.1016/j.vetpar.2015.08.024
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Abstract: Leishmania (Leishmania) infantum is the cause of visceral leishmaniasis in the Americas. The disease is transmitted mostly through the bite of the invertebrate vector, the phlebotomine Lutzomyia longipalpis in the New World. Although the domestic dog is considered the most important reservoir of the disease, other mammalian, including wildlife, are susceptible to infection. The goal of this study was to perform xenodiagnosis to evaluate the capacity of naturally infected maned wolves (Chrysocyon brachyurus) an… Show more

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Cited by 17 publications
(18 citation statements)
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“…In addition to the neoplasm, this maned wolf was infected with Leishmania infantum. Visceral leishmaniasis is endemic in the area were the zoological garden is located (Mol et al, 2015). Likely the splenic amyloidosis and glomerulopathy may be due to Leishmania infection, as previously described in wild canids (Luppi et al, 2008).…”
Section: Discussionmentioning
confidence: 66%
See 1 more Smart Citation
“…In addition to the neoplasm, this maned wolf was infected with Leishmania infantum. Visceral leishmaniasis is endemic in the area were the zoological garden is located (Mol et al, 2015). Likely the splenic amyloidosis and glomerulopathy may be due to Leishmania infection, as previously described in wild canids (Luppi et al, 2008).…”
Section: Discussionmentioning
confidence: 66%
“…The wolf was originally from the zoological garden in Goiania (Brazil), and kept in captivity at the Fundação Zoo-Botânica de Belo Horizonte (Belo Horizonte, Brazil) since 2008. The animal had been previously diagnosed with visceral leishmaniasis (Mol et al, 2015), and in January 2015 developed severe myiasis in the right ear, followed by prostration and death.…”
Section: Case Reportmentioning
confidence: 99%
“…In general, leishmaniasis chemotherapy is very complex not only for dogs, but also for humans [58]. Given the prohibition of treating dogs with the same drugs used to treat humans in Brazil for a long period,a great mission capacity of L. (L.) infantum from maned wolves (Chrysocyon brachyurus) and vinegar dogs (Speothos venaticus) infected without symptoms to invertebrate hosts, probably sustaining the natural parasitic cycle [42]. In South America, especially in Brazil, the presence of L. (L.) infantum has been described in marsupials and rodents [43] and canids with a large territorial distribution, such as the crab-eating fox (Cerdocyon thous), hoary fox (Lycalopex vetulus), Chrysocyon brachyurus and Speothos venaticus [44,45].…”
Section: Challenges and Perspectivesmentioning
confidence: 99%
“…To date, approximately 1000 phlebotomine species have been described worldwide (Vivero et al, 2015;Galati et al, 2017). Among them, only those of the genera Lutzomyia and Phlebotomus are responsible for Leishmania transmission (Bray et al, 2014;Mol et al, 2015).…”
Section: Introductionmentioning
confidence: 99%