2013
DOI: 10.1097/qai.0b013e31829202a2
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Abstract: Early achievements in biomedical approaches for HIV prevention included physical barriers (condoms), clean injection equipment (both for medical use and for injection drug users), blood and blood product safety, and prevention of mother to child transmission. In recent years, antiretroviral drugs to reduce risk of transmission (when the infected person takes the medicines; treatment as prevention or TasP) or reduce risk of acquisition (when the seronegative person takes them; pre-exposure prophylaxis or PrEP) … Show more

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Cited by 34 publications
(27 citation statements)
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References 268 publications
(161 reference statements)
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“…Within the past decade, there have been significant advances in HIV/AIDS treatment and prevention options [1]. Globally, the importance of anti-retroviral therapy to reduce mother-to-infant transmission [2] and transmission between sexual partners [3,4] as well as post-exposure prophylaxis for needle-stick injuries [5] and high-risk sexual exposure [6,7] are well recognized.…”
Section: Introductionmentioning
confidence: 99%
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“…Within the past decade, there have been significant advances in HIV/AIDS treatment and prevention options [1]. Globally, the importance of anti-retroviral therapy to reduce mother-to-infant transmission [2] and transmission between sexual partners [3,4] as well as post-exposure prophylaxis for needle-stick injuries [5] and high-risk sexual exposure [6,7] are well recognized.…”
Section: Introductionmentioning
confidence: 99%
“…Globally a steadily increasing number of persons have access to treatment, although this number remains below 50% of those infected [16]. Appropriately, these important scientific breakthroughs and public health achievements have been widely heralded [1,17-20] and have led to more nuanced approaches of combination prevention [18,19,21] and/or treatment as prevention [22]. However, as impressive as these advances and opportunities are, there is widespread recognition of the growing need for identifying and addressing the issues involved in maintaining the effectiveness of these programs as they move from research to the public health arena.…”
Section: Introductionmentioning
confidence: 99%
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“…4 Male circumcision significantly reduces the risk of contracting HIV, but it has not been evaluated in low-prevalence settings and may not be acceptable to some uncircumcised men. 5 The fourth and potentially most feasible strategy for clinicians and high-risk, HIV-negative patients is preexposure prophylaxis (PrEP)-the use of daily antiretroviral medication to reduce the risk of acquiring HIV infection. In May 2014 the Centers for Disease Control and Prevention (CDC) published updated practice guidelines recommending the use of PrEP with daily oral dosing of tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) (Truvada; Gilead Sciences, Foster City, CA) for this indication.…”
mentioning
confidence: 99%
“…Observational data suggest the impact of health communication to date, but perhaps, the most crucial challenges and most telling evidence will come from work on the continuum of care that is being rolled out in "treatment as prevention" initiatives, preexposure prophylaxis, voluntary medical male circumcision, and combination prevention initiatives. [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47] Integration of behavioral approaches facilitated by health communication into these biomedical approaches will determine the degree, and speed, of their success. The true test of all HIV prevention and treatment efforts is whether, working in concert, they reduce HIV incidence, transmission rates, and deaths.…”
Section: Discussionmentioning
confidence: 99%