Transition to propofol after sevoflurane anesthesia to prevent emergence agitation: a randomized controlled trial

Costi, David; Ellwood, James; Wallace, Andrew; Ahmed, Samira; Waring, Lynne; Cyna, Allan M

doi:10.1111/pan.12617

Cited by 61 publications

(47 citation statements)

References 18 publications

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“…As a result of this, 45 articles published from 1999 to 2015 were complied with the selection criteria (Fig. 1)5678910111213141516171819202122232425262728293031323334353637383940414243444546474849. A total of 4,032 cases were included and the detailed baseline characteristics of the included studies were displayed in Table 1.…”

Section: Resultsmentioning

confidence: 99%

Efficacy and Acceptability of Different Auxiliary Drugs in Pediatric Sevoflurane Anesthesia: A Network Meta-analysis of Mixed Treatment Comparisons

Wang

Huang

Gao

et al. 2016

Sci Rep

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Emergence agitation preventive medicine should be combined with pediatric anesthesia because of the high frequency of emergence agitation. However, it is challenging to determine the most appropriate medication that can be introduced into pediatric anesthesia for the sake of emergence agitation prevention. We reviewed and retrieved the data from PubMed and Embase. Various medications were assessed based on several endpoints including Emergence agitation outcomes (EA), postoperative nausea and vomiting (PONV), the number of patients who required analgesic (RA), pediatric anesthesia emergence delirium (PAED), the extubation time, the emergency time and the duration of post-anesthesia care unit (PACU) stay. Both traditional and network meta-analysis were carried in this study. A total of 45 articles were complied with the selection criteria and the corresponding articles were reviewed. Fentanyl demonstrated the highest cumulative ranking probability which was followed by those of ketamine and dexmedetomidine with respect to EA and PAED. When PONV and RA were concerned together, clonidine exhibited the highest cumulative ranking probability compared to other medications. Our study suggested that dexmedetomidine perhaps is the most appropriate prophylactic treatment which can be introduced into anesthesia for preventing emergence agitation.

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Section: Resultsmentioning

confidence: 99%

Efficacy and Acceptability of Different Auxiliary Drugs in Pediatric Sevoflurane Anesthesia: A Network Meta-analysis of Mixed Treatment Comparisons

Wang

Huang

Gao

et al. 2016

Sci Rep

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“…23 Specifically, the use of propofol at the end of general anesthesia appears to reduce the incidence of ED and improve the quality of emergence. 24 While all of these studies have attempted to reduce the prevalence of ED in children undergoing surgical procedures, there has been no definitive measure in successfully eliminating ED in children.…”

Section: Discussionmentioning

confidence: 99%

Comparing incidence of emergence delirium between sevoflurane and desflurane in children following routine otolaryngology procedures

et al. 2017

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“…However, the mean score of pain was lower in the propofol group than isoflurane group. Furthermore, transition to propofol after sevoflurane anesthesia to prevent emergence agitation is recomeneded by Costi et al19 Moreover, co-administration of sevoflurane/propofol provides better recovery than sevoflurane in combined general/epidural anesthesia 20. Therefore, using isoflurane with propofol might be more effective for surgeries that need to anesthesia.…”

Section: Discussionmentioning

confidence: 99%

Effect of intravenous anesthesia with propofol versus isoflurane inhalation anesthesia in postoperative pain of inguinal herniotomy: a randomized clinical trial

et al. 2017

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Postoperative pain is a common problem after inguinal herniotomy. We aimed to compare the intravenous anesthesia effects of propofol and isoflurane inhalation anesthesia on postoperative pain after inguinal herniotomy. In a randomized clinical trial, 102 eligible patients were selected based on inclusion and exclusion criteria and were randomly divided in two groups. In the first group, propofol was used for the maintenance of anesthesia, while isoflurane was used in the second group. The patient’s heart rate, systolic and diastolic blood pressure and oxygen saturation before, during and after surgery, recovery time and postoperative pain were measured immediately, 2, 4 and 6 hours after surgery and compared between two groups. T-test, and repeated measurement test were used for statistical analysis. No statistically significant differences were observed in heart rate, blood pressure and oxygen saturation levels between the two groups (P > 0.05). Propofol has higher effect in easing postoperative pain of patients than isoflurane, but no difference in postoperative complications, including chills, nausea and vomiting, occurs in both two groups. Propofol is effective in declining the postoperative pain of patients after anesthesia in comparison with isoflurane. Moreover, due to the antioxidant, anti-inflammatory and analgesic properties of propofol, it is preferred to isoflurane and the authors recommended it to be used.

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Transition to propofol after sevoflurane anesthesia to prevent emergence agitation: a randomized controlled trial

Abstract: Transition to propofol at the end of sevoflurane anesthesia reduces the incidence of EA and improves the quality of emergence. There is a small increase in recovery time, but no delay in discharge home.

Cited by 61 publications

References 18 publications

Efficacy and Acceptability of Different Auxiliary Drugs in Pediatric Sevoflurane Anesthesia: A Network Meta-analysis of Mixed Treatment Comparisons

Efficacy and Acceptability of Different Auxiliary Drugs in Pediatric Sevoflurane Anesthesia: A Network Meta-analysis of Mixed Treatment Comparisons

Comparing incidence of emergence delirium between sevoflurane and desflurane in children following routine otolaryngology procedures

Effect of intravenous anesthesia with propofol versus isoflurane inhalation anesthesia in postoperative pain of inguinal herniotomy: a randomized clinical trial

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