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Cited by 65 publications
(18 citation statements)
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“…Prolonged severe unconjugated hyperbilirubinaemia may also be due to the presence of conjugation inhibitors in maternal serum (Arias et al, 1965 normally found in maternal serum and breast milk, to the degree of neonatal jaundice.…”
mentioning
confidence: 99%
“…Prolonged severe unconjugated hyperbilirubinaemia may also be due to the presence of conjugation inhibitors in maternal serum (Arias et al, 1965 normally found in maternal serum and breast milk, to the degree of neonatal jaundice.…”
mentioning
confidence: 99%
“…The inhibitory effect of maternal milk on bilirubin glucuronidation increases on storage and is destroyed by heating at 56 o C. 246 Maternal Serum Jaundice. In this condition, termed LuceyDriscoll syndrome, 247,248 jaundice occurs within the first 4 days of life. Peak serum bilirubin concentrations of 8.9-65 mg/dl are reached within 7 days.…”
Section: Bilirubin Conjugationmentioning
confidence: 99%
“…In older children and adults, serum bilirubin concentrations range from 2 to 22 mg/dl and, up to the prcsent time, none of patients with the type I1 disorder has been shown t o develop kernicterus after the neonatal period. The type I1 syndrome may be differentiated from type I by: (1) lower serum bilirubin concentrations after the neonatal period; (2) normal stool color; (3) higher bilirubin concentrations of approximately 50 mg/dl in duodenal bile; and (4) positive response to phenobarbital treatment. 2 Hepatic glucuronyl transferase activity in type I1 syndrome patients is barely detectable.…”
Section: Inherited Defects In Bilirubin Conjugationmentioning
confidence: 99%
“…In these infants use of phototherapy only serves to prolong hospitalization and separation of infant from mother. Newborn infants with any of the following conditions or complications, however, should receive either prophylactic or therapeutic phototherapy irrespective of their maturity: (1) development of serious complications in association with a previous exchange transfusion; (2) marginal functional reserve in cardiorespiratory status; (3) expectation of multiple exchange transfusions following the initial exchange, such as in severe hemolytic disease; (4) unavailability of a safe route of catheter placement for exchange, such as in abdominal surgery. gastroschisis, omphalocele; and (5) possible graft versus host reaction from exchange transfusion, such as in acquired or inherited immune disorders.…”
Section: Specific Therapiesmentioning
confidence: 99%