Transient Evoked Otoacoustic Emissions in Two-month-old Infants: A Normative Study

Driscoll, Carlie; Kei, Joseph; Murdoch, Bruce E.; McPherson, Bradley; Smyth, Veronica; Latham, Simon; Loscher, J

doi:10.3109/00206099909073021

Cited by 21 publications

(14 citation statements)

References 23 publications

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“…The ear asymmetry effect is evident in spontaneous otoacoustic emissions (SOAEs), with the right ear producing stronger emissions than the left ear [13,14,29]. Studies of TEOAEs have also shown significantly larger emissions in the right in comparison with the left ear [18][19][20]30]. Most of the studies did not show an ear asymmetry effect in DPOAE, except for one study of Keogh et al, where the results revealed a small but significant difference in signal-to-noise ratio (SNR) between ears, with right ears showing a higher mean SNR than left ears at 1.9, 3.0, 3.8, and 6.0 kHz [6].…”

Section: Introductionmentioning

confidence: 97%

“…Females have higher incidence of spontaneous otoacoustic emissions than in men (typically 58 versus 22%, respectively) [13][14][15][16][17]. Many studies also indicate a gender effect, whereby stronger TEOAEs are observed in females across many age groups from infancy to childhood [5,15,[17][18][19][20][21][22]. Gender differences were also found in DPOAE [15,17,[23][24][25].…”

Section: Introductionmentioning

confidence: 97%

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A normative study of otoacoustic emissions, ear asymmetry, and gender effect in healthy schoolchildren in Slovakia

Pavlovčinová

Jakubı́ková

Trnovec

et al. 2010

International Journal of Pediatric Otorhinolaryngology

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Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 97%

A normative study of otoacoustic emissions, ear asymmetry, and gender effect in healthy schoolchildren in Slovakia

Pavlovčinová

Jakubı́ková

Trnovec

et al. 2010

International Journal of Pediatric Otorhinolaryngology

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“…Females appear to generate stronger and higher numbers of OAEs than males. This sex difference in emission strength and frequency is present directly after birth (Aidan, Lestang, Avan, & Bonfils, 1997;Berninger, 2007;Burns, Arehart, & Campbell, 1992;Cassidy & Ditty, 2001;Driscoll et al, 1999;Kei, McPherson, Smyth, Latham, & Loscher, 1997;Saitoh et al, 2006;Strickland, Burns, & Tubis, 1985;Thornton, Marotta, & Kennedy, 2003). The outer hair cells of the cochlea have been reported to develop between the 9th and 22nd week of gestation (Lavigne-Rebillard & Pujol, 1986;Pujol & Lavigne-Rebillard, 1995), a time window that overlaps with the critical period for sexual differentiation, when testosterone levels in male fetuses are elevated (Finegan, Bartleman, & Wong, 1989).…”

Section: Introductionmentioning

confidence: 99%

Click-Evoked Otoacoustic Emissions in Children and Adolescents with Gender Identity Disorder

et al. 2014

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Click-evoked otoacoustic emissions (CEOAEs) are echo-like sounds that are produced by the inner ear in response to click-stimuli. CEOAEs generally have a higher amplitude in women compared to men and neonates already show a similar sex difference in CEOAEs. Weaker responses in males are proposed to originate from elevated levels of testosterone during perinatal sexual differentiation. Therefore, CEOAEs may be usedas a retrospective indicator of someone's perinatal androgen environment. Individuals diagnosed with Gender Identity Disorder (GID), according to DSM-IV-TR, are characterized by a strong identification with the other gender and discomfort about their natal sex. Although the etiology of GID is far from established, itishypothesizedthat atypicallevels of sexsteroids during a critical period of sexual differentiation of the brain might play a role. In the present study, we compared CEOAEs in treatmentnaïve children and adolescents with early-onset GID (24 natal boys, 23 natal girls) and control subjects (65 boys, 62 girls). We replicated the sex difference in CEOAE response amplitude in the control group. This sex difference, however, was not present in the GID groups. Boys with GID showed stronger, more female-typical CEOAEs whereas girls with GID did not differ in emissionstrengthcomparedtocontrolgirls.Basedontheassumption that CEOAE amplitude can be seen as an index of relative androgen exposure,our results provide some evidence for the idea that boys with GID may have been exposed to lower amounts of androgen during early development in comparison to control boys.

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“…Third, the findings of some tests are affected by environmental and/or physiologic noise, resulting in false positive outcomes. In particular, physiologic noise in neonates could confound TEOAE and DPOAE results (Driscoll et al 1999). The AABR test is susceptible to myogenic noise from neonates, resulting in false positive responses (Herrman et al 1995 studied the test performance of WBA to predict DPOAE outcomes in 324 neonates and reported an AROC of 0.90 for WBA at 2 kHz and 0.82 for WBA at 1 kHz.…”

Section: Resultsmentioning

confidence: 99%

Wideband absorbance measures in neonates and young infants

Aithal¹

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Evaluation of middle ear status in young infants is a challenge in both screening and diagnostic contexts due to a lack of valid and objective tools of middle ear assessment . The standard tools used to determine the middle ear status in older children are neither efficient nor accurate in evaluating young infants.Wideband absorbance (WBA) is recommended as a tool for middle ear assessment in young infants due to its time efficiency, reliability, objectivity and ability WBA. The neonates were tested prior to their discharge from the hospital. In addition, a total of 36, 30, 33 and 30 infants were seen at 1, 2, 4, and 6 months of age, respectively. These infants were tested using HFT, DPOAE and WBA.The results revealed that conductive hearing loss was common among infants referred through NHS. Australian Aboriginal infants had significantly higher rates of middle ear pathology and conductive hearing loss at birth and showed poor resolution of middle ear pathology over time compared to non-Aboriginal infants. Use of a test of middle ear function (eg. WBA) as an adjunct to the screening tool to facilitate management and prioritisation of infants for further testing was recommended (Chapter Two). Normative ambient pressure WBA data were established for 66 neonates who passed a test battery of AABR, HFT, ASR, TEOAE and DPOAE tests. There was a significant difference in WBA across frequencies from 250 to 8000 Hz (Chapter Three). Test performance of WBA was compared across four single tests and five test battery reference standards in 192 neonates. The test performance of WBA against the test battery reference standards was better than that against single test reference standards (Chapter Four). Despite equal pass rates as determined by a test battery of HFT and DPOAE, the WBA of Aboriginal neonates who passed the test battery was significantly lower suggesting that Aboriginal neonates had more significant outer/middle ear conditions than Caucasian neonates. WBA appeared to be more sensitive to middle ear status than test battery comprising HFT and DPOAE (Chapter Five). In a cross sectional study of infants, developmental effects were evident during the first six months of life, with WBA reducing with age. Although data from the study could be used as reference standard for detecting middle ear disorders, further development of age-specific normative WBA was recommended (Chapter Six).

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Transient Evoked Otoacoustic Emissions in Two-month-old Infants: A Normative Study

Cited by 21 publications

References 23 publications

A normative study of otoacoustic emissions, ear asymmetry, and gender effect in healthy schoolchildren in Slovakia

A normative study of otoacoustic emissions, ear asymmetry, and gender effect in healthy schoolchildren in Slovakia

Click-Evoked Otoacoustic Emissions in Children and Adolescents with Gender Identity Disorder

Wideband absorbance measures in neonates and young infants

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