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Cited by 348 publications
(313 citation statements)
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References 110 publications
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“…Zudem können Fehltransfusionen durchgeführt und extrem selten trotz hoher Sicherheitsbemühungen Viren, Parasiten oder Prionen übertragen werden [1].…”
unclassified
“…Zudem können Fehltransfusionen durchgeführt und extrem selten trotz hoher Sicherheitsbemühungen Viren, Parasiten oder Prionen übertragen werden [1].…”
unclassified
“…In such cases, intravenous immunoglobulin (IVIG) and Erythropoietin (EPO) should be administered concurrently [7]. For severe cases, EPO-Eculizumab should be considered [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. In cases where additional transfusions are necessary, EPO-Rituximab may prove successful [3].…”
Section: Discussionmentioning
confidence: 99%
“…HS typically causes a fall in absolute reticulocyte count (a decrease from the baseline concentration) during hemolysis, and a rise in Hb and reticulocyte counts often accompanies recovery [2,5]. Delayed reactions typically result from a secondary immune response in a previously transfused or pregnant patient who has developed an alloantibody, and such reactions can be life-threatening [7,8]. The risk of developing DHTR is the most serious consequence of alloimmunization in SCD patients.…”
Section: Introductionmentioning
confidence: 99%
“…This reaction typically occurs in patients with hemoglobinopathies and has been reported in 1-19% of transfusions in patients with SCD [6]. Although mechanistically not well understood, it is likely a complication of alloimmunization, with possible contribution of an underlying genetic predisposition [7,8].…”
Section: Consequences Of Alloimmunizationmentioning
confidence: 99%