Transforming Growth Factor Beta

S100β protein stimulates regeneration of the rabbit cornea

“…Edema in superficial stromal layers; weakening of cell-cell lecular interaction of S100 proteins with oligopeptides and proteins, including the regulators of cell growth, proliferation, and differentiation [2,4]. In this connection it is interesting that the transforming ~ growth factor, belonging to the family of epidermal growth factors, promotes healing of corneal-scleral wounds [ 13]. S100b proteins modulate the activity of some protein kinases and phosphoprotein phosphatases, and are thus able to exert an effect upon phosphorylation/dephosphorylation of a number of cytoplasmic and nuclear protein substrates [4].…”

S100β protein stimulates regeneration of the rabbit cornea

“…Edema in superficial stromal layers; weakening of cell-cell lecular interaction of S100 proteins with oligopeptides and proteins, including the regulators of cell growth, proliferation, and differentiation [2,4]. In this connection it is interesting that the transforming ~ growth factor, belonging to the family of epidermal growth factors, promotes healing of corneal-scleral wounds [ 13]. S100b proteins modulate the activity of some protein kinases and phosphoprotein phosphatases, and are thus able to exert an effect upon phosphorylation/dephosphorylation of a number of cytoplasmic and nuclear protein substrates [4].…”

Plasma Rich in Growth Factors in Macular Hole Surgery

“…Before surgery with PRGF, seventy-five per cent of eyes were pseudophakic (n = 6). The initial BCVA (logMAR) for the MMH group was 0.837 ± 0.383 (0.523-1.000) and the initial IOP was 13.3 ± 1.3 (12)(13)(14)(15). In the OCT measurements, it was found that the overall mean of the base diameter was 1181.6 ± 345.7 (673.0-1577.0) µm, for the minimum diameter it was 516.9 ± 154.7 (313.0-806.0) µm, and for the height it was 462.8 ± 58.1 (380.0-519.0) µm.…”

Hydromassage of macular hole edges for large and persistent full-thickness macular holes

“…In this way, it remains a challenge to effectively close the hole. Smiddy et al [10] described the use of transforming growth factor-2 as an adhesive to assist in the closure of the MH. Analogously, autologous serum, platelets have been introduced into the procedure afterward [11] .…”

S100β protein stimulates regeneration of the rabbit cornea

“…Edema in superficial stromal layers; weakening of cell-cell lecular interaction of S100 proteins with oligopeptides and proteins, including the regulators of cell growth, proliferation, and differentiation [2,4]. In this connection it is interesting that the transforming ~ growth factor, belonging to the family of epidermal growth factors, promotes healing of corneal-scleral wounds [ 13]. S100b proteins modulate the activity of some protein kinases and phosphoprotein phosphatases, and are thus able to exert an effect upon phosphorylation/dephosphorylation of a number of cytoplasmic and nuclear protein substrates [4].…”

Plasma Rich in Growth Factors in Macular Hole Surgery

“…Before surgery with PRGF, seventy-five per cent of eyes were pseudophakic (n = 6). The initial BCVA (logMAR) for the MMH group was 0.837 ± 0.383 (0.523-1.000) and the initial IOP was 13.3 ± 1.3 (12)(13)(14)(15). In the OCT measurements, it was found that the overall mean of the base diameter was 1181.6 ± 345.7 (673.0-1577.0) µm, for the minimum diameter it was 516.9 ± 154.7 (313.0-806.0) µm, and for the height it was 462.8 ± 58.1 (380.0-519.0) µm.…”

Hydromassage of macular hole edges for large and persistent full-thickness macular holes

“…In this way, it remains a challenge to effectively close the hole. Smiddy et al [10] described the use of transforming growth factor-2 as an adhesive to assist in the closure of the MH. Analogously, autologous serum, platelets have been introduced into the procedure afterward [11] .…”

S100β protein stimulates regeneration of the rabbit cornea

“…Edema in superficial stromal layers; weakening of cell-cell lecular interaction of S100 proteins with oligopeptides and proteins, including the regulators of cell growth, proliferation, and differentiation [2,4]. In this connection it is interesting that the transforming ~ growth factor, belonging to the family of epidermal growth factors, promotes healing of corneal-scleral wounds [ 13]. S100b proteins modulate the activity of some protein kinases and phosphoprotein phosphatases, and are thus able to exert an effect upon phosphorylation/dephosphorylation of a number of cytoplasmic and nuclear protein substrates [4].…”

Plasma Rich in Growth Factors in Macular Hole Surgery

“…Before surgery with PRGF, seventy-five per cent of eyes were pseudophakic (n = 6). The initial BCVA (logMAR) for the MMH group was 0.837 ± 0.383 (0.523-1.000) and the initial IOP was 13.3 ± 1.3 (12)(13)(14)(15). In the OCT measurements, it was found that the overall mean of the base diameter was 1181.6 ± 345.7 (673.0-1577.0) µm, for the minimum diameter it was 516.9 ± 154.7 (313.0-806.0) µm, and for the height it was 462.8 ± 58.1 (380.0-519.0) µm.…”

Hydromassage of macular hole edges for large and persistent full-thickness macular holes

“…In this way, it remains a challenge to effectively close the hole. Smiddy et al [10] described the use of transforming growth factor-2 as an adhesive to assist in the closure of the MH. Analogously, autologous serum, platelets have been introduced into the procedure afterward [11] .…”