Transbronchial Needle Aspiration in Diagnosing Intrathoracic Tuberculous Lymphadenitis

Bilaçeroğlu, Semra; ̈nel, O ̈zden Gu; Eris, Nur; Çağırıcı, Ufuk; Mehta, Atul C.

doi:10.1378/chest.126.1.259

Cited by 78 publications

(70 citation statements)

References 29 publications

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“…BILACEROGLU [41] A number of hilar-mediastinal pathological processes besides sarcoidosis have been identified using TBNA. The following diseases have been assessed by TBNA: tuberculous adenitis [43]; lymphoma [35,36]; post-transplantation lymphoproliferative disorder [44]; thymoma [45]; and carcinoid [46] metastases from nonlung cancer diseases [4]. The specificity of the technique is very high (96-100%) [40,46], although falsepositive results have been reported [47,48].…”

Section: Resultsmentioning

confidence: 99%

Transbronchial and transoesophageal (ultrasound-guided) needle aspirations for the analysis of mediastinal lesions

Herth

Rabe²,

Gasparini³

et al. 2006

European Respiratory Journal

136

103

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A tissue diagnosis of mediastinal nodes is frequently needed for accurate lung cancer staging as well as the assessment of mediastinal masses. Transbronchial needle aspiration (TBNA) is a safe procedure that is performed during routine bronchoscopy. Provided mediastinal metastases are confirmed, TBNA has a high impact on patient management. Unfortunately, TBNA remains underused in current daily practice, mainly due to the lack of realtime needle visualisation. The introduction of echo-endoscopes has overcome this problem.Endobronchial ultrasound-guided TBNA (EBUS-TBNA) allows real-time controlled tissue sampling of paratracheal, subcarinal and hilar lymph nodes. Mediastinal lymph nodes located adjacent to the oesophagus can be assessed by transoesophageal ultrasound-guided fine needle aspiration (EUS-FNA). Owing to the complementary reach of EBUS-TBNA and EUS-FNA in assessing different regions of the mediastinum, recent studies suggest that complete and accurate mediastinal staging can be achieved by the combination of both procedures.It is expected that implementation of minimally invasive endoscopic methods of endobronchial ultrasound-guided transbronchial needle aspiration and transoesophageal ultrasound-guided fine needle aspiration will reduce the need for surgical staging of lung cancer significantly.

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Section: Resultsmentioning

confidence: 99%

Transbronchial and transoesophageal (ultrasound-guided) needle aspirations for the analysis of mediastinal lesions

Herth

Rabe²,

Gasparini³

et al. 2006

European Respiratory Journal

136

103

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“…With this technique, specimens are collected by inserting a 19-gauge flexible histology needle through a bronchoscopy tube; patients are sedated but conscious, and computed tomography scans are used for guidance. 31 …”

Section: Alternativesmentioning

confidence: 99%

Tuberculosis: Pathophysiology, Clinical Features, and Diagnosis

Knechel

2009

Critical Care Nurse

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“…TBNA has been used safely and effectively to obtain cytological specimens from mediastinal lymph nodes for the diagnosis and staging of bronchogenic carcinoma .20 yrs [5]. However, the published data on mediastinal tuberculous lymphadenitis diagnosed by TBNA is more limited [6][7][8]. With cytological analysis, TBNA can confirm the presence of granulomatous inflammation at sites that are readily accessible outside the CNS.…”

Section: Discussionmentioning

confidence: 99%

The use of thoracic computed tomography scanning and EBUS-TBNA to diagnose tuberculosis of the central nervous system: two case reports

Mehta

Connell

Wickremasinghe

et al. 2010

European Respiratory Review

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Herein, we report two cases of tuberculosis (TB) of the central nervous system where accessing the cerebrospinal fluid for diagnostic purposes was relatively or absolutely contraindicated at presentation.The finding of mediastinal lymphadenopathy on thoracic computed tomography scans, which was not visible on plain chest radiography, allowed endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of these lymph nodes to support the diagnosis of TB in each patient and rule out other disease processes.EBUS-TBNA is a new bronchoscopic technique and in this case report appears to be a safe and useful option in the diagnosis of TB. Moreover, it proved to be so in cases where the main focus of disease was outside the thorax.

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Transbronchial Needle Aspiration in Diagnosing Intrathoracic Tuberculous Lymphadenitis

Cited by 78 publications

References 29 publications

Transbronchial and transoesophageal (ultrasound-guided) needle aspirations for the analysis of mediastinal lesions

Transbronchial and transoesophageal (ultrasound-guided) needle aspirations for the analysis of mediastinal lesions

Tuberculosis: Pathophysiology, Clinical Features, and Diagnosis

The use of thoracic computed tomography scanning and EBUS-TBNA to diagnose tuberculosis of the central nervous system: two case reports

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