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Cited by 16 publications
(15 citation statements)
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“…DEB-TACE, as an alternative choice for unresectable cancer, shows an advantage of increased local chemotherapy concentration and sustained release of antitumor drugs [14][15][16][17]. CB is the first polyvinyl alcohol microsphere product developed in China, which can load several kinds of chemotherapeutic drugs, including irinotecan.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…DEB-TACE, as an alternative choice for unresectable cancer, shows an advantage of increased local chemotherapy concentration and sustained release of antitumor drugs [14][15][16][17]. CB is the first polyvinyl alcohol microsphere product developed in China, which can load several kinds of chemotherapeutic drugs, including irinotecan.…”
Section: Discussionmentioning
confidence: 99%
“…Transarterial chemoembolization (TACE) and drugeluting bead TACE (DEB-TACE) are alternative treatments for chemotherapy refractory patients with GALM [12,13]. As a novel drug-delivering device, DEB-TACE showed a advantage of increased local chemotherapy concentration and sustained release of anti-tumor drugs [14][15][16][17]. Previous studies have indicated that DEB-TACE with Callispheres ® beads (CB) is safe and effective in many types of malignant tumors [18][19][20].…”
Section: Introductionmentioning
confidence: 99%
“…Currently, DEB-TACE has been widely used in the treatment of unresectable carcinoma of substantial organs (e.g. liver 6 , 7 , uterus 8 or lung 9 ) rather than cavity organs such as bladder and digestive tract 3 , 15 . Our results indicated that DEB-TACE using doxorubicin-loaded CB is feasible, safe and showed good short-term efficacy without serious adverse events.…”
Section: Discussionmentioning
confidence: 99%
“…Transarterial chemoembolization (TACE) is a palliative treatment option for unresectable RCC, which may increase the clinical efficacy and decrease adverse events than systemic chemotherapy by increasing local drug concentration 1 . Emulsions of chemotherapeutic drugs and lipiodol were usually used in traditional TACE; however, drugs can neither release slowly nor reside long enough time 2 As a novel drug delivery and embolization system, drug-eluting beads TACE (DEB-TACE) is able to release drugs slowly into the malignant tissue after embolizing the tumor-feeding arteries 3 5 . CalliSpheres beads (CB) has been used recently for patients with hepatocellular carcinoma 6 , 7 , uterus 8 or lung 9 .…”
Section: Introductionmentioning
confidence: 99%
“…CalliSpheres ® have a similar chemical structure and application property to DC Bead, but at a lower price [12]. Previous studies have investigated the drug loading of some classic antitumor agents to CalliSpheres ® , such as doxorubicin [13], oxaliplatin [14], irinotecan [15], and vinorelbine [16]. However, the drug delivery ability of IDA has not yet been reported.…”
Section: Introductionmentioning
confidence: 99%