Tracking the Near Eastern origins and European dispersal of the western house mouse

Cucchi, Thomas; Papayianni, Katerina; Cersoy, Sophie; Aznar-Cormano, Laetitia; Zazzo, Antoine; Debruyne, Régis; Berthon, Rémi; Bălășescu, Adrian; Simmons, Alan H.; Valla, François; Hamilakis, Yannis; Mavridis, Fanis; Mashkour, Marjan; Darvish, Jamshid; Siahsarvi, Roohollah; Biglari, Fereidoun; Petrie, Cameron A.; Weeks, Lloyd; Sardari, Alireza; Maziar, Sepideh; Denys, Christiane; Orton, David; Jenkins, Emma; Zeder, Melinda A.; Searle, Jeremy B.; Larson, Greger; Bonhomme, François; Auffray, Jean‐Christophe; Vigne, Jean‐Denis

doi:10.1038/s41598-020-64939-9

Cited by 57 publications

(54 citation statements)

References 80 publications

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“…Rodents, the most abundant and diversi ed order of living mammals (~ 40% of mammalian biodiversity; Burgin et al 2018), are undoubtedly the vertebrate group that has most often accompanied humans throughout their history of global dispersal (e.g. Cucchi et al 2020). The ever-increasing intensi cation of human enterprise (e.g.…”

Section: Introductionmentioning

confidence: 99%

Economic costs of invasive rodents worldwide: the tip of the iceberg

Diagne

Ballesteros‐Mejia

Bodey

et al. 2021

Preprint

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Rodents are a notorious group of invaders worldwide. Their invasions have substantially impacted native ecosystems, local infrastructure, and human health and well-being. However, a lack of synthesized estimation of their economic impacts hampers effective management interventions at relevant scales. Here, we used the InvaCost database – the most up-to-date and comprehensive synthesis of reported monetary invasion costs – to assess the economic costs of invasive rodents globally. Our conservative analysis showed that reported costs of rodent invasions reached at least US$ 3.28 billion between 1930 and 2018, and were significantly increasing through time. The highest species-specific costs were reported from Ondatra zibethicus, Rattus norvegicus and Castor canadensis, with over 90% of the total costs damage-related, principally impacting agriculture, and predominantly reported in Asia (65%) and Europe (20%). Although minimal compared to damages, the majority of management investments were made on islands, with post-invasion spending always dominant. Importantly, managements expenditures to prevent rodent invasions were entirely absent from mainland areas. However, only approximately one quarter of the 48 known invasive alien rodents had reported costs, highlighting clear taxonomic biases. Obvious cost reporting gaps were also evidenced across different areas, sectors and contexts, suggesting a great underestimation of the costs incurred by invasive rodents globally. Greater and integrative research effort on the direct and indirect costs of rodent invaders – particularly the distinction between native rodent pests and invasive rodents’ impacts, or from indirect impacts on human health – would be crucial for bridging these gaps. Ultimately, this would support proactive and sustainable management strategies.

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Section: Introductionmentioning

confidence: 99%

Economic costs of invasive rodents worldwide: the tip of the iceberg

Diagne

Ballesteros‐Mejia

Bodey

et al. 2021

Preprint

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“…The Western European M. m. domesticus populations are derived from Iranian populations and invaded Western Europe about 3,000 y ago, where they quickly radiated. The split from the Iranian population would have occurred no more than 10,000 y ago ( 30 , 31 ). This provides a time line to estimate retroCNV emergence rates by comparing the population and lineage-specific retroCNVs, under the assumption that they represent mostly new retroposition events in their lineage.…”

Section: Resultsmentioning

confidence: 99%

The mutational load in natural populations is significantly affected by high primary rates of retroposition

Zhang

Xie

Ullrich

et al. 2021

Proc. Natl. Acad. Sci. U.S.A.

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Gene retroposition is known to contribute to patterns of gene evolution and adaptations. However, possible negative effects of gene retroposition remain largely unexplored since most previous studies have focused on between-species comparisons where negatively selected copies are mostly not observed, as they are quickly lost from populations. Here, we show for natural house mouse populations that the primary rate of retroposition is orders of magnitude higher than the long-term rate. Comparisons with single-nucleotide polymorphism distribution patterns in the same populations show that most retroposition events are deleterious. Transcriptomic profiling analysis shows that new retroposed copies become easily subject to transcription and have an influence on the expression levels of their parental genes, especially when transcribed in the antisense direction. Our results imply that the impact of retroposition on the mutational load has been highly underestimated in natural populations. This has additional implications for strategies of disease allele detection in humans.

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“…The Western European M. m. domesticus populations are derived from Iranian (IR) populations and invaded Western Europe about 3,000 years ago where they quickly radiated. The split from the Iranian population would have occurred no more than 10,000 years ago (30, 31). This provides a time line to estimate retroCNV emergence rates by comparing the population and lineage-specific retroCNVs, under the assumption that they represent mostly new retroposition events in their lineage.…”

Section: Resultsmentioning

confidence: 99%

The mutational load in natural populations is significantly affected by high primary rates of retroposition

Zhang

Xie

Ullrich

et al. 2020

Preprint

View full text Add to dashboard Cite

Gene retroposition is known to contribute to patterns of gene evolution and adaptations. However, possible negative effects of gene retroposition remain largely unexplored, since most previous studies have focussed on between-species comparisons where negatively selected copies are mostly not observed, as they are quickly lost from the populations. Here, we show for natural house mouse populations that the primary rate of retroposition is orders of magnitude higher than previously thought. Comparisons with SNP distribution patterns in the same populations show that most retroposition events are deleterious. Transcriptomic profiling analysis shows that new retroposed copies become easily subject to transcription and have an influence on the expression level of their parental genes, especially when transcribed in the antisense direction. Our results imply that the impact of retroposition on the mutational load in natural populations has been highly underestimated, which has also major implications for strategies of disease allele detection in humans.

show abstract

Tracking the Near Eastern origins and European dispersal of the western house mouse

Cited by 57 publications

References 80 publications

Economic costs of invasive rodents worldwide: the tip of the iceberg

Economic costs of invasive rodents worldwide: the tip of the iceberg

The mutational load in natural populations is significantly affected by high primary rates of retroposition

The mutational load in natural populations is significantly affected by high primary rates of retroposition

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