Toxoplasma gondii infections in birds, companion, food and recreational animals in Nigeria: A systematic review and meta-analysis

Karshima, Solomon Ngutor; Karshima, Magdalene Nguvan; Karaye, Gloria Pisha; Oziegbe, Stanley David

doi:10.1016/j.vprsr.2020.100418

Cited by 3 publications

(2 citation statements)

References 87 publications

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“…They are considered good carriers or reservoirs for infectious agents due to their high dispersal capabilities. According to the published literature, T. gondii prevalence has increased in several bird species ( Cooper et al, 2015 ; Dubey, 2002 ; Dubey et al, 2010 ; Karshima et al, 2020 ; Nie et al, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Global prevalence of Toxoplasma gondii in birds: A systematic review and meta-analysis

Zaki,

Olfatifar,

Ghaffarifar

et al. 2024

Parasite Epidemiology and Control

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Section: Introductionmentioning

confidence: 99%

Global prevalence of Toxoplasma gondii in birds: A systematic review and meta-analysis

Zaki,

Olfatifar,

Ghaffarifar

et al. 2024

Parasite Epidemiology and Control

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“…Surveys based upon seroprevalence using pigs and chickens indicate a high level of T . gondii occurrence [ 2 , 3 , 5 , 7 , 23 , 24 , 25 , 26 ], but population genetic data is scarce. In addition, there is a similar dearth of information regarding the T .…”

Section: Introductionmentioning

confidence: 99%

Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria

et al. 2021

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Toxoplasma gondii parasites present strong but geographically varied signatures of population structure. Populations sampled from Europe and North America have commonly been defined by over-representation of a small number of clonal types, in contrast to greater diversity in South America. The occurrence and extent of genetic diversity in African T. gondii populations remains understudied, undermining assessments of risk and transmission. The present study was designed to establish the occurrence, genotype and phylogeny of T. gondii in meat samples collected from livestock produced for human consumption (free-range chickens, n = 173; pigs, n = 211), comparing with T. gondii detected in blood samples collected from seropositive pregnant women (n = 91) in Benue state, Nigeria. The presence of T. gondii DNA was determined using a published nested polymerase chain reaction, targeting the 529 bp multicopy gene element. Samples with the highest parasite load (assessed using quantitative PCR) were selected for PCR-restriction fragment length polymorphism (PCR-RFLP) targeting the surface antigen 3 (SAG3), SAG2 (5’ and 3’), beta-tubulin (BTUB) and dense granule protein 6 (GRA6) loci, and the apicoplast genome (Apico). Toxoplasma gondii DNA was detected in all three of the populations sampled, presenting 30.6, 31.3 and 25.3% occurrence in free-range chickens, pigs and seropositive pregnant women, respectively. Quantitative-PCR indicated low parasite occurrence in most positive samples, limiting some further molecular analyses. PCR-RFLP results suggested that T. gondii circulating in the sampled populations presented with a type II genetic background, although all included a hybrid type I/II or II/III haplotype. Concatenation of aligned RFLP amplicon sequences revealed limited diversity with nine haplotypes and little indication of host species-specific or spatially distributed sub-populations. Samples collected from humans shared haplotypes with free-range chickens and/or pigs. Africa remains under-explored for T. gondii genetic diversity and this study provides the first detailed definition of haplotypes circulating in human and animal populations in Nigeria.

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Seroprevalence and risk factors of Toxoplasma gondii in sheep and goats of North West Province, South Africa

Masombuka,

Mphuthi,

Ngoshe

et al. 2024

BMC Vet Res

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Background The protozoan parasite Toxoplasma gondii causes toxoplasmosis, one of the most prevalent parasitic zoonotic diseases with significant economic and public health implications worldwide. Infection with the parasite has a significant adverse effect on sheep and goat production and can frequently go undetected in the herd, resulting in abortions and weak or dead offspring. Although there are few studies on seroprevalence and risk factors associated with T. gondii infections in livestock in other provinces of South Africa, there is no data in the North West province. Therefore, a cross-sectional study was conducted to investigate the seroprevalence of T. gondii and risk factors associated with exposure in sheep and goats of the North West province of South Africa. Sera from 439 livestock (164 sheep and 285 goats) were collected and analysed for the presence of T. gondii IgG antibodies using indirect ELISA (Enzyme-linked immunosorbent assay). An assessment of potential risk factors in farms associated with seropositivity was also conducted using a structured questionnaire. Results Out of the 439 tested sheep and goats, 13.9% (61/439) were positive for IgG antibodies against T. gondii. Sheep and goats had seroprevalences of 19.5% (32/164) and 10.5% (29/275) respectively. In the multivariable logistic regression model, the risk of acquiring T. gondii was significantly higher in the mixed breed [Odds ratio (OR) = 71.07; 95% confidence interval (CI): 266.8-1893.1; p < 0.011)] animals than white dorper sheep and in farms that burn or bury aborted material (OR = 42.04; CI: 179.9-982.5; p = 0.020) compared to those that only burn aborted material. The risk was lower for the farms in Kagisano-Molopo (OR = 0.00; CI: 0.0-25.4; p = 0.015) and Mahikeng (OR = 0.00; CI: 0.0-4.9; p < 0.001) local municipalities than Greater Taung local municipality, and for the animals that drink water from dams (OR = 0.03; CI: 0.2–58.8; p = 0.021) than those that drink from boreholes. Conclusion The seroprevalence and risk factors associated with transmission observed show that T. gondii infection is widespread in sheep and goats of the North West province.

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Toxoplasma gondii infections in birds, companion, food and recreational animals in Nigeria: A systematic review and meta-analysis

Cited by 3 publications

References 87 publications

Global prevalence of Toxoplasma gondii in birds: A systematic review and meta-analysis

Global prevalence of Toxoplasma gondii in birds: A systematic review and meta-analysis

Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria

Seroprevalence and risk factors of Toxoplasma gondii in sheep and goats of North West Province, South Africa

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