Toxic Psychosis Following Use of Stilbamidine in Blastomycosis

Vital Statistics and Medical Research

“…Like trichlo¬ roethylene, stilbamidine has been reported to give relief in tic douloureux.5 Toxic psychosis has been reported following stilbamidine therapy; however, the patient was emotionally disturbed prior to administration of the drug. 6 Recently, Snapper has reported on the use of 2-hydroxystilbamidine in blastomycosis.7 Previous work had led him to conclude that this compound is more stable in solution than stilbamidine and does not produce tri¬ geminal neuropathy. Encouraging improvement was re¬ ported in three cases of systemic blastomycosis and one case of the cutaneous form of the disease.…”