Towards the Antimicrobial Finishing of Poly(isoprene)

Abstract

Summary: Anionically polymerised (poly)isoprene was functionalized with cysteamine applying thiol-ene click chemistry. Subsequent quaternisation of the primary amino groups gave polymers with antimicrobial activity against Listeria monocytogenes, Eschericchia coli, Pseudomonas fluorescens and Staphylococcus aureus as revealed from tests performed according to the Japanese Industrial Standard Z2801:2000. The novel polymers feature sufficient thermal stability for the compounding with commodity polymers such as poly(propylene) and might be used as a non leaching additive to finish commodity polymers with antimicrobial acitivity.

Potentially biocompatible polyacrylamides derived by the Ugi four-component reaction

“…The Ugi-derived monomers exhibit a related structure, which suggests similar applications for them. Thus, the synthesized polymers were tested for their biological compatibility by a modified Japanese Industrial Standard Z 2801:2000 protocol [43,44,48]. This test consists in the exposition of different bacterial strains to polymer coated glass slides for 16 h at 30°C.…”