Towards a Casa Segura: A Consumer Product Study of the Effect of Insecticide-Treated Curtains on Aedes aegypti and Dengue Virus Infections in the Home

Loroño-Pino, María Alba; García-Rejón, Julián E.; Machaín-Williams, Carlos; Gómez-Carro, Salvador; Nuñez-Ayala, Guadalupe; Nájera-Vázquez, Maria del Rosario; Losoya, Arturo; Aguilar, Lyla; Saavedra-Rodríguez, Karla; Lozano-Fuentes, Saúl; Beaty, Meaghan K.; Black, William C.; Keefe, Thomas J.; Eisen, Lars; Beaty, Barry J.

doi:10.4269/ajtmh.12-0772

Cited by 46 publications

(80 citation statements)

References 48 publications

(54 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…aegypti females were described previously (Loroño-Pino et al 2013). Study homes distributed across ~30 neighborhoods (Colonias) in the southern and eastern parts of Mérida City were followed over a 15-month period from May 2009–July 2010.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Temporal Correlations Between Mosquito-Based Dengue Virus Surveillance Measures or Indoor Mosquito Abundance and Dengue Case Numbers in Mérida City, México

Eisen¹,

García-Rejón²,

Gómez-Carro³

et al. 2014

J Med Entomol

Self Cite

View full text Add to dashboard Cite

Surveillance of dengue virus (DENV) in Aedes (Stegomyia) aegypti (L.) females is of potential interest because human DENV infections are commonly asymptomatic, which decreases the effectiveness of dengue case surveillance to provide early warning of building outbreaks. Our primary aim was to examine if mosquito-based virological measures – monthly percentages of examined Ae. aegypti females infected with DENV or examined homes from which ≥1 DENV-infected Ae. aegypti female was collected – are correlated with reported dengue cases in the same or subsequent months within study neighborhoods in Mérida City, México. The study encompassed ~30 neighborhoods in the southern and eastern parts of the city. Mosquitoes were collected monthly over a 15-month period within study homes (average of 145 homes examined per month); this produced ~5,800 Ae. aegypti females subsequently examined for DENV RNA. Although monthly dengue case numbers in the study neighborhoods varied more than 100-fold during the study period, we did not find statistically significant positive correlations between monthly data for mosquito-based DENV surveillance measures and reported dengue cases in the same or subsequent months. Monthly average temperature, rainfall, and indoor abundance of Ae. aegypti females were positively correlated (P ≤ 0.001) with dengue case numbers in subsequent months with lag times of 3–5, 2, and 1–2 months, respectively. However, because dengue outbreak risk is strongly influenced by serotype-specific susceptibility of the human population to DENV, the value of weather conditions and entomological indices to predict outbreaks is very limited. Potential ways to improve the sensitivity of mosquito-based DENV surveillance are discussed.

show abstract

Section: Methodsmentioning

confidence: 99%

“…aegypti and intradomicillary DENV transmission (Loroño-Pino et al 2013), we performed monthly indoor collections of Ae. aegypti females (typically in >125 homes/month) and determined their DENV infection status.…”

Section: Introductionmentioning

confidence: 99%

Temporal Correlations Between Mosquito-Based Dengue Virus Surveillance Measures or Indoor Mosquito Abundance and Dengue Case Numbers in Mérida City, México

Eisen¹,

García-Rejón²,

Gómez-Carro³

et al. 2014

J Med Entomol

Self Cite

View full text Add to dashboard Cite

show abstract

“…aegypti is ubiquitous in large urban centers and in smaller communities 2 and dengue is hyperendemic. 3,4 The mosquito is controlled through a combination of physical source reduction (removal or alteration of potential water-holding containers) and use of insecticides including the organophosphate temephos to eliminate larvae from water-holding containers and since 2000 pyrethroids have been used to control adults in and around homes. 5,6 Although insecticide pressure is high in large urban centers in Yucatan State, fine-scale refugia from insecticides are present.…”

Section: Introductionmentioning

confidence: 99%

“…aegypti. 4,9 Another para mutation that is also strongly implicated in pyrethroid resistance involves a cysteine replacement (C1,534). 10,11 Our goal in this study is to test two alternative hypotheses concerning the evolution and spread of pyrethroid resistance in Yucatan State, Mexico.…”

Section: Introductionmentioning

confidence: 99%

Local Evolution of Pyrethroid Resistance Offsets Gene Flow Among Aedes aegypti Collections in Yucatan State, Mexico

Saavedra-Rodríguez¹,

Beaty²,

Lozano-Fuentes³

et al. 2015

The American Society of Tropical Medicine and Hygiene

Self Cite

View full text Add to dashboard Cite

Abstract. The mosquito Aedes aegypti is the major vector of the four serotypes of dengue virus (DENV1-4). Previous studies have shown that Ae. aegypti in Mexico have a high effective migration rate and that gene flow occurs among populations that are up to 150 km apart. Since 2000, pyrethroids have been widely used for suppression of Ae. aegypti in cities in Mexico. In Yucatan State in particular, pyrethroids have been applied in and around dengue case households creating an opportunity for local selection and evolution of resistance. Herein, we test for evidence of local adaptation by comparing patterns of variation among 27 Ae. aegypti collections at 13 single nucleotide polymorphisms (SNPs): two in the voltage-gated sodium channel gene para known to confer knockdown resistance, three in detoxification genes previously associated with pyrethroid resistance, and eight in putatively neutral loci. The SNPs in para varied greatly in frequency among collections, whereas SNPs at the remaining 11 loci showed little variation supporting previous evidence for extensive local gene flow. Among Ae. aegypti in Yucatan State, Mexico, local adaptation to pyrethroids appears to offset the homogenizing effects of gene flow.

show abstract

“…Mosquito-borne dengue is a major health problem in the Yucatán Peninsula of México (Loroño-Pino et al 1993, 2004, 2013; García-Rejón et al 2008). Several studies reported on the immature or adult stage of the primary local vector mosquito, Aedes ( Stegomyia ) aegypti (L.), for dengue virus.…”

Section: Introductionmentioning

confidence: 99%

Urban Mosquito Fauna in Mérida City, México: Immatures Collected from Containers and Storm-Water Drains/Catch Basins

Baak-Baak

Arana-Guardia

Cigarroa-Toledo

et al. 2014

Southwestern Entomologist

Self Cite

View full text Add to dashboard Cite

We examined the species composition and temporal occurrence of immature mosquitoes in containers and storm-water drains/catch basins from November 2011 to June 2013 in Mérida City, México. A wide range of urban settings were examined, including residential premises, vacant lots, parking lots, and streets or sidewalks with storm-water drains/catch basins. In total, 111,776 specimens of 15 species were recorded. The most commonly collected species were Aedes (Stegomyia) aegypti (L.) (n = 60,961) and Culex quinquefasciatus Say (45,702), which together accounted for 95.4% of the immatures collected. These species were commonly encountered during both rainy and dry seasons, whereas most other mosquito species were collected primarily during the rainy season. Other species collected were Aedes (Howardina) cozumelensis Diaz Najera, Aedes (Ochlerotatus) taeniorhynchus (Wiedemann), Aedes (Ochlerotatus) trivittatus (Coquillett), Culex coronator Dyar and Knab, Culex interrogator Dyar and Knab, Culex lactator Dyar and Knab, Culex nigripalpus Theobald, Culex salinarius Coquillett, Culex tarsalis Coquillett, Culex thriambus Dyar, Haemagogus equinus Theobald, Limatus durhamii Theobald, and Toxorhynchites rutilus (Coquillett). The greatest number of species was recorded from vacant lots (n = 11), followed by storm-water drains/catch basins (nine) and residential premises (six). Our study demonstrated that the heterogeneous urban environment in Mérida City supports a wide range of mosquito species, many of which are nuisance biters of humans and/or capable of serving as vectors of pathogens affecting humans or domestic animals. We also briefly reviewed the medical importance of the encountered mosquito species.

show abstract

Towards a Casa Segura: A Consumer Product Study of the Effect of Insecticide-Treated Curtains on Aedes aegypti and Dengue Virus Infections in the Home

Cited by 46 publications

References 48 publications

Temporal Correlations Between Mosquito-Based Dengue Virus Surveillance Measures or Indoor Mosquito Abundance and Dengue Case Numbers in Mérida City, México

Temporal Correlations Between Mosquito-Based Dengue Virus Surveillance Measures or Indoor Mosquito Abundance and Dengue Case Numbers in Mérida City, México

Local Evolution of Pyrethroid Resistance Offsets Gene Flow Among Aedes aegypti Collections in Yucatan State, Mexico

Urban Mosquito Fauna in Mérida City, México: Immatures Collected from Containers and Storm-Water Drains/Catch Basins

Contact Info

Product

Resources

About