Total intravenous anaesthesia with propofol or inhalational anaesthesia with isoflurane for major abdominal surgery: Recovery characteristics and postoperative oxygenation—an international multicentre study

Phillips, A. S.; Mirakhur, R. K.; Glen, J. B.; Hunter, S.

doi:10.1111/j.1365-2044.1996.tb15005.x

Cited by 21 publications

(12 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous studies have demonstrated significant changes in systemic hemodynamics [32] and systemic oxygenation [33] during and immediately following major surgery, which may potentially alter ocular oxygenation. Since blood is drawn from the femoral artery to monitor systemic arterial PO 2 and establish the physiologic condition of animals during experiments, it is beneficial to determine the effect of this surgical procedure on retinal oxygenation.…”

Section: Discussionmentioning

confidence: 99%

Chorioretinal Vascular Oxygen Tension in Spontaneously Breathing Anesthetized Rats

et al. 2007

View full text Add to dashboard Cite

Purpose: To establish baseline and variability of oxygen tension (PO₂) measurements in the choroid, retinal arteries, capillaries, and veins of spontaneously breathing anesthetized rats and determine the effect of a moderate surgical procedure on the chorioretinal PO₂. Methods: Our previously established optical section phosphorescence imaging technique was utilized to measure PO₂ in the chorioretinal vasculatures. Imaging was performed in 29 spontaneously breathing rats under ketamine/xylazine anesthesia. In 7 rats, blood was drawn using a surgically implanted femoral arterial catheter and analyzed to determine the systemic arterial PO₂. The PO₂ measurements in 22 rats without surgery (group 1) and 7 surgically instrumented rats (group 2) were statistically compared. The intrasubject variability was calculated by the average standard deviation (SD) of repeated measurements. Results: The average systemic arterial PO₂ was 52 ± 7 mm Hg (mean ± SD) in group 2. In group 1, the average PO₂ measurements in the choroid, retinal arteries, capillaries, and veins were 50 ± 11, 40 ± 5, 39 ± 6, and 30 ± 5 mm Hg, respectively. No statistically significant PO₂ differences in any of the chorioretinal vasculatures were found between the two groups (p > 0.4). The intrasubject variability was 3 mm Hg in the choroid, retinal arteries, capillaries, and veins. Conclusions: Chorioretinal PO₂ measurements in spontaneously breathing anesthetized rats have a relatively low variability, indicating that PO₂ changes due to various physiological alterations can be reliably assessed.

show abstract

Section: Discussionmentioning

confidence: 99%

Chorioretinal Vascular Oxygen Tension in Spontaneously Breathing Anesthetized Rats

et al. 2007

View full text Add to dashboard Cite

show abstract

“…However, hypoxia, defined as an S p O 2 of less than 94%, was observed for 1–1.5% of the duration of measurement in this study in both groups. Low oxygen saturations are a common occurrence in the postoperative period after major surgery even in the absence of intrathecal or extradural opioids [22, 23]. The low incidence and the lesser degree of postoperative desaturation in our and other obstetric studies is probably due to the lower abdominal nature of the surgery and lower intra‐abdominal pressure after delivery of the baby.…”

Section: Discussionmentioning

confidence: 76%

Intrathecal diamorphine for analgesia after Caesarean sectionA dose finding study and assessment of side‐effects

1998

Self Cite

View full text Add to dashboard Cite

SummaryEighty women undergoing elective Caesarean section under spinal anaesthesia using hyperbaric bupivacaine 0.5% were randomly allocated to receive, in addition, intrathecal diamorphine 0.125, 0.25 or 0.375 mg or saline. Postoperative morphine requirements, measured using a patientcontrolled analgesia system, were reduced in a dose-dependent manner by diamorphine. Pain scores were significantly lower at 2 and 6 h following the two larger doses of diamorphine. Less supplemental analgesia was required intra-operatively if intrathecal diamorphine had been given. The incidences of vomiting and pruritus were also dose-related. No respiratory rates of less than 14 breath.min ¹1 were recorded and the incidence of oxygen saturation readings less than 95% and 90% did not differ between groups. There were no adverse neonatal effects. Intrathecal diamorphine in the present study was found to be safe in doses of up to 0.375 mg following Caesarean section. However, minor side-effects were frequently observed.

show abstract

“…Transition from sedation to anaesthesia by TCI is smooth and simple, and permits improved haemodynamic stability compared with other methods [23]. Total intravenous anaesthesia, with a propofol/opioid‐based technique allows faster emergence with superior recovery [24] compared with volatile‐based anaesthesia [25]. This is especially important in the immediate postoperative management of a patient with a difficult airway.…”

Section: Discussionmentioning

confidence: 99%

Awake tracheal intubation with the intubating laryngeal mask in a patient with diffuse idiopathic skeletal hyperostosis

Palmer

Ball

2000

Anaesthesia

View full text Add to dashboard Cite

SummaryDiffuse idiopathic skeletal hyperostosis, otherwise known as Forestier's disease or ankylosing hyperostosis, is a relatively common condition that is distinguished from ankylosing spondylitis by the relative preservation of spinal function and the characteristic 'candle flame' lipping of the vertebrae. We report a patient with this condition and a well-recorded history of impossible intubation who presented for emergency laparotomy. The patient was intubated awake using the intubating laryngeal mask and sedation and anaesthesia were provided by a target-controlled infusion of propofol. Awake fibreoptic intubation has become a key technique in dealing with the anticipated difficult intubation. The recent National Confidential Enquiry into Perioperative Deaths (NCEPOD) [1] has recommended that a fibrescope and personnel skilled in its use are available in all sites where anaesthesia is performed. However, fibreoptic intubation is not a panacea, and difficult fibreoptic intubation is an ever-present problem. The intubating laryngeal mask (ILM), a purpose designed modification of the familiar laryngeal mask airway with a curved steel inlet tube and integral introducing handle, has been used successfully to intubate the trachea in cases of fixed neck deformity [2]. We report its successful use in an awake patient, with diffuse idiopathic skeletal hyperostosis (DISH) and an acute abdominal emergency, in whom there was a recorded history of difficult fibreoptic intubation. Case historyA 48-year-old woman, BMI 34.2, complaining of diarrhoea, vomiting and lower abdominal pain, was presented for anaesthetic assessment and urgent laparotomy. She was reported by the surgical registrar as being 'an anaesthetic nightmare'. Previous medical history included endometriosis, low back pain, migraine and an alaplasty to enlarge her nares. Anaesthetic notes were available from 1994 and 1995 when she had laparoscopies. Three failed intubations were recorded. On one occasion anaesthesia had been abandoned, in another a laryngeal mask airway had been used to maintain the airway during surgery and in a third case an ENT consultant had used a fibrescope to intubate the trachea after induction of anaesthesia. This procedure had been reported as being extremely difficult. View at direct laryngoscopy had been graded as Cormack and Lehane IV by one anaesthetist and another had noted 'impossible direct laryngoscopy due to a small mouth, full set of teeth, large tonsils and a rigid cervical spine'.On examination she appeared well hydrated and, apart from a flushed appearance and a sinus tachycardia of 100 beat.min À1 , not unduly unwell. Examination of the airway revealed that she had a short neck with almost no extension and rotation limited to 30Њ in either direction. She had an interincisor gap of 31 mm, her modified Mallampati score was 4 and thyromental distance 5 cm (Fig. 1). She was hyperteloric and her posterior hairline was only 2.5 cm above the vertebra prominens. Lateral cervical spine radiographs showed a short cervical sp...

show abstract

Total intravenous anaesthesia with propofol or inhalational anaesthesia with isoflurane for major abdominal surgery: Recovery characteristics and postoperative oxygenation—an international multicentre study

Abstract: SummaryTwo hundred und teri

Cited by 21 publications

References 25 publications

Chorioretinal Vascular Oxygen Tension in Spontaneously Breathing Anesthetized Rats

Chorioretinal Vascular Oxygen Tension in Spontaneously Breathing Anesthetized Rats

Intrathecal diamorphine for analgesia after Caesarean sectionA dose finding study and assessment of side‐effects

Awake tracheal intubation with the intubating laryngeal mask in a patient with diffuse idiopathic skeletal hyperostosis

Contact Info

Product

Resources

About