Total Anomalous Pulmonary Venous Connection: An Analysis of Current Management Strategies in a Single Institution

Friesen, Camille L. Hancock; Zurakowski, David; Thiagarajan, Ravi R.; Forbess, Joseph M.; Nido, Pedro J. del; Mayer, John E.; Jonas, Richard A.

doi:10.1016/j.athoracsur.2004.07.005

Cited by 211 publications

(253 citation statements)

References 16 publications

Supporting

Mentioning

226

Contrasting

Unclassified

Order By: Relevance

“…Low body weight at repair is not a risk factor for mortality, and such observation has also been described in other reports [4,14,15]. In our series, surgery was performed as soon as possible after diagnosis was confirmed, regardless of body weight and age.…”

Section: Discussionmentioning

confidence: 73%

See 1 more Smart Citation

Risk Factors of Total Anomalous Pulmonary Venous Connection Surgery

Wu¹,

Kan²,

Wu³

et al. 2016

Ped Health Res

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 73%

“…We put these risk factors to simple Cox regression analysis and noted a significant correlation (p=0.002, Table 3). In previous studies, low cardiac output syndrome was also reported as the main causes of early postoperative death [14,[16][17][18].…”

Section: Discussionmentioning

confidence: 99%

Risk Factors of Total Anomalous Pulmonary Venous Connection Surgery

Wu¹,

Kan²,

Wu³

et al. 2016

Ped Health Res

View full text Add to dashboard Cite

show abstract

“…The hemodynamic criterion for PVO was a mean gradient across the stenosis of 4 mm Hg or more. 7 All available pathological reports were also studied.On the basis of the evaluation of all available data (including operative reports), patients were classified as either having or not having evidence of PVO at presentation. A severity grade was ascribed as follows: 1, Severe obstruction requiring immediate intervention; 2, obstruction present but clinically stable, not requiring immediate intervention; and 3, no significant obstruction.…”

mentioning

confidence: 99%

Total Anomalous Pulmonary Venous Connection

Seale

Uemura²,

Webber³

et al. 2010

Circulation

234

View full text Add to dashboard Cite

on behalf of the British Congenital Cardiac AssociationBackground-Late mortality after repair of total anomalous pulmonary venous connection is frequently associated with pulmonary venous obstruction (PVO). We aimed to describe the morphological spectrum of total anomalous pulmonary venous connection and identify risk factors for death and postoperative PVO. Methods and Results-We conducted a retrospective, international, collaborative, population-based study involving all 19 pediatric cardiac centers in the United Kingdom, Ireland, and Sweden. All infants with total anomalous pulmonary venous connection born between 1998 and 2004 were identified. Cases with functionally univentricular circulations or atrial isomerism were excluded. All available data and imaging were reviewed. Of 422 live-born cases, 205 (48.6%) had supracardiac, 110 (26.1%) had infracardiac, 67 (15.9%) had cardiac, and 37 (8.8%) had mixed connections. There were 2 cases (0.5%) of common pulmonary vein atresia. Some patients had extremely hypoplastic veins or, rarely, discrete stenosis of the individual veins. Sixty (14.2%) had associated cardiac anomalies. Sixteen died before intervention. Three-year survival for surgically treated patients was 85.2% (95% confidence interval 81.3% to 88.4%). Risk factors for death in multivariable analysis comprised earlier age at surgery, hypoplastic/stenotic pulmonary veins, associated complex cardiac lesions, postoperative pulmonary hypertension, and postoperative PVO. Sixty (14.8%) of the 406 patients undergoing total anomalous pulmonary venous connection repair had postoperative PVO that required reintervention. Three-year survival after initial surgery for patients with postoperative PVO was 58.7% (95% confidence interval 46.2% to 69.2%). Risk factors for postoperative PVO comprised preoperative hypoplastic/stenotic pulmonary veins and absence of a common confluence. Key Words: follow-up studies Ⅲ pulmonary veins Ⅲ pulmonary vein stenosis Ⅲ heart defects, congenital T otal anomalous pulmonary venous connection (TAPVC) is a rare form of congenital heart disease in which all pulmonary veins connect to the systemic veins, right atrium, or coronary sinus. TAPVC can occur in conjunction with a wide variety of cardiac malformations, especially atrial isomerism. Before the advent of cardiac surgery, almost all of these children died in the first few months of life. With treatment, there has been continued improvement in the mortality and morbidity of isolated TAPVC. [1][2][3][4] This can be attributed to progress in surgical expertise and to developments in intensive care such as use of nitric oxide and extracorporeal membrane oxygenation, which have led to salvage of the sickest neonates. Conclusions-Preoperative Clinical Perspective on p 2726Nevertheless, there is an ongoing late mortality in patients with TAPVC. It is frequently associated with postoperative pulmonary venous obstruction (PVO), with an incidence of 5% to 18%. [1][2][3][5][6][7][8][9] Postoperative PVO may be a consequence of an inadequate ana...

show abstract

“…In case of TAPVC, the pulmonary venous obstruction may occur. It is present in 48%-55% of the cases and is more frequent in supracardiac and infracardiac types, due to the longer and more complicated way that blood needs to pass in order to reach the heart 9,10 . In order to prevent the increase of pulmonary blood pressure and consequent decrease of blood saturation leading to neonatal death, neonates with TAPVC and pulmonary venous obstruction should be delivered in a tertiary center and need to undergo a surgical intervention during the first hours after birth.…”

Section: Discussionmentioning

confidence: 99%

Prenatal Diagnosis of TAPVC on Monday, Delivery of Tuesday and Cardiac Surgery at Wednesday - A Model of Perinatal Care in 3rd Trimester in Case of Fetal/Neonatal Critical Heart Defect in Tertiary Center.

Respondek-Liberska

Sokołowski

Słodki

et al. 2016

Prenatal Cardiology

View full text Add to dashboard Cite

Total anomalous pulmonary venous connection (TAPVC) is a congenital heart defect (CHD), in which all pulmonary veins connect to the systemic veins or to the right atrium/coronary sinus instead of the left atrium. We present a case report of fetus with prenatally diagnosed isolated infracardiac type of TAPVC in 38th week of gestation. In fetal echocardiographic examination performed in the Department of Prenatal Cardiology, the fetus presented lack of visible pulmonary veins connection to left atrium, abnormal venous confluence behind left atrium, additional vein leading from abdominal cavity to mediastinum and abnormal smooth Doppler blood flow in pulmonary confluence. The accurate prenatal diagnosis allowed to deliver the neonate at term, in tertiary center one day after diagnosis, and to perform surgical reposition of pulmonary veins the following day. The neonate was referred home in a good condition after 28 days of hospitalization. This case is a good example of the value of the 3rd trimester echocardiography. Key words: total anomalous pulmonary venous return, prenatal diagnosis, fetal echocardiographyCorresponding author: l.sokolowski90@gmail.com Submitted: 2016Submitted: -06-30, accepted: 2016 INTRODUCTIONTotal anomalous pulmonary venous connection (TAPVC) is a congenital heart defect (CHD), in which all pulmonary veins connect to the systemic veins or to the right atrium/ coronary sinus instead of the left atrium. TAPVC is a relatively rare pathology.

show abstract

Total Anomalous Pulmonary Venous Connection: An Analysis of Current Management Strategies in a Single Institution

Cited by 211 publications

References 16 publications

Risk Factors of Total Anomalous Pulmonary Venous Connection Surgery

Risk Factors of Total Anomalous Pulmonary Venous Connection Surgery

Total Anomalous Pulmonary Venous Connection

Prenatal Diagnosis of TAPVC on Monday, Delivery of Tuesday and Cardiac Surgery at Wednesday - A Model of Perinatal Care in 3rd Trimester in Case of Fetal/Neonatal Critical Heart Defect in Tertiary Center.

Contact Info

Product

Resources

About