“…It may either cause a severe sensitization dermatitis or aggravate an existing condi¬ tion without producing a definite dermatitis. 13 What, however, is more important with regard to both peni¬ cillin and the sulfonamide drugs is the fact that such locally produced sensitivity frequently leads to a gen¬ eralized sensitivity. This may be of such a high degree as later to prevent the internal use of these valuable therapeutic agents.…”
“…It may either cause a severe sensitization dermatitis or aggravate an existing condi¬ tion without producing a definite dermatitis. 13 What, however, is more important with regard to both peni¬ cillin and the sulfonamide drugs is the fact that such locally produced sensitivity frequently leads to a gen¬ eralized sensitivity. This may be of such a high degree as later to prevent the internal use of these valuable therapeutic agents.…”
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