Topical Timolol Decreases Plasma High-Density Lipoprotein Cholesterol Level

Blood Lipid Profile in Primary Open-Angle Glaucoma: A Biochemical Analysis Study

“…They suggested, however, that not only co-medications may modify the association of TGs and glaucoma, but also medications used for glaucoma treatment. Importantly, topical β-blockers, which are a cornerstone treatment for glaucoma, have been shown to increase systemic TG levels in a study on 28 healthy volunteers taking topical timolol (40). Consistently, the present study revealed significantly higher TG levels in POAG patients than in the control group.…”

Blood Lipid Profile in Primary Open-Angle Glaucoma: A Biochemical Analysis Study

“…They suggested, however, that not only co-medications may modify the association of TGs and glaucoma, but also medications used for glaucoma treatment. Importantly, topical β-blockers, which are a cornerstone treatment for glaucoma, have been shown to increase systemic TG levels in a study on 28 healthy volunteers taking topical timolol (40). Consistently, the present study revealed significantly higher TG levels in POAG patients than in the control group.…”

Prevalence of Primary Open-Angle Glaucoma and its Relationship with Smoking in the Population of the Azar Cohort: A Cross-Sectional Study

“…[ 25 ] case–control study in Iran, a significant relationship was found between TG >150 mg/dl and POAG. In contrast, two separate case–control studies in Bosnia[ 27 ] and Poland[ 28 ] found no association between blood TG levels and POAG.…”

“…On the other hand, none of these studies has examined the relationship between blood TG and POAG separately in the two genders. None of these studies, like ours, have considered drugs that people with POAG and hypertriglyceridemia receive, although these drugs, including topical beta-blockers[ 28 ] and statins,[ 29 ] could affect this association.…”

Triglycerides and Open Angle Glaucoma – A Meta-analysis with meta-regression

“…However, not only co-medications may modify the association of triglycerides and glaucoma, but also medications used for glaucoma treatment. Importantly, topical beta-blockers, which are a cornerstone treatment for glaucoma, have been shown to increase systemic triglyceride levels in a study on 28 healthy volunteers taking topical timolol 20 . Given the fact that it is very likely that the patients in this meta-analysis had a high prevalence of topical beta-blocker use, this may have increased the difference in triglyceride levels between patients and controls.…”

Blood Lipid Profile in Primary Open-Angle Glaucoma: A Biochemical Analysis Study

“…They suggested, however, that not only co-medications may modify the association of TGs and glaucoma, but also medications used for glaucoma treatment. Importantly, topical β-blockers, which are a cornerstone treatment for glaucoma, have been shown to increase systemic TG levels in a study on 28 healthy volunteers taking topical timolol (40). Consistently, the present study revealed significantly higher TG levels in POAG patients than in the control group.…”

Prevalence of Primary Open-Angle Glaucoma and its Relationship with Smoking in the Population of the Azar Cohort: A Cross-Sectional Study

“…[ 25 ] case–control study in Iran, a significant relationship was found between TG >150 mg/dl and POAG. In contrast, two separate case–control studies in Bosnia[ 27 ] and Poland[ 28 ] found no association between blood TG levels and POAG.…”

“…On the other hand, none of these studies has examined the relationship between blood TG and POAG separately in the two genders. None of these studies, like ours, have considered drugs that people with POAG and hypertriglyceridemia receive, although these drugs, including topical beta-blockers[ 28 ] and statins,[ 29 ] could affect this association.…”

Triglycerides and Open Angle Glaucoma – A Meta-analysis with meta-regression

“…However, not only co-medications may modify the association of triglycerides and glaucoma, but also medications used for glaucoma treatment. Importantly, topical beta-blockers, which are a cornerstone treatment for glaucoma, have been shown to increase systemic triglyceride levels in a study on 28 healthy volunteers taking topical timolol 20 . Given the fact that it is very likely that the patients in this meta-analysis had a high prevalence of topical beta-blocker use, this may have increased the difference in triglyceride levels between patients and controls.…”

Blood Lipid Profile in Primary Open-Angle Glaucoma: A Biochemical Analysis Study

“…They suggested, however, that not only co-medications may modify the association of TGs and glaucoma, but also medications used for glaucoma treatment. Importantly, topical β-blockers, which are a cornerstone treatment for glaucoma, have been shown to increase systemic TG levels in a study on 28 healthy volunteers taking topical timolol (40). Consistently, the present study revealed significantly higher TG levels in POAG patients than in the control group.…”

Prevalence of Primary Open-Angle Glaucoma and its Relationship with Smoking in the Population of the Azar Cohort: A Cross-Sectional Study

“…[ 25 ] case–control study in Iran, a significant relationship was found between TG >150 mg/dl and POAG. In contrast, two separate case–control studies in Bosnia[ 27 ] and Poland[ 28 ] found no association between blood TG levels and POAG.…”

“…On the other hand, none of these studies has examined the relationship between blood TG and POAG separately in the two genders. None of these studies, like ours, have considered drugs that people with POAG and hypertriglyceridemia receive, although these drugs, including topical beta-blockers[ 28 ] and statins,[ 29 ] could affect this association.…”

Triglycerides and Open Angle Glaucoma – A Meta-analysis with meta-regression

“…However, not only co-medications may modify the association of triglycerides and glaucoma, but also medications used for glaucoma treatment. Importantly, topical beta-blockers, which are a cornerstone treatment for glaucoma, have been shown to increase systemic triglyceride levels in a study on 28 healthy volunteers taking topical timolol 20 . Given the fact that it is very likely that the patients in this meta-analysis had a high prevalence of topical beta-blocker use, this may have increased the difference in triglyceride levels between patients and controls.…”