2002
Topical Targretin and Intralesional Interferon Alfa for Cutaneous Lymphoma of the Scalp
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2003
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Cited by 16 publications
(11 citation statements)
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“…Radiotherapy alone has been used in patients with localized B-cell PCNHL with the relapse rates ranging between 32% and 100% (3,(9)(10)(11). There are reports of intralesional administration of interferon alfa, cisplatin and bexarotene (tegretin) (11,12). Zenone et al presented one patient who had complete remission with intralesional interferon alfa ( 11).…”
Section: Discussionmentioning
confidence: 99%
“…Radiotherapy alone has been used in patients with localized B-cell PCNHL with the relapse rates ranging between 32% and 100% (3,(9)(10)(11). There are reports of intralesional administration of interferon alfa, cisplatin and bexarotene (tegretin) (11,12). Zenone et al presented one patient who had complete remission with intralesional interferon alfa ( 11).…”
Section: Discussionmentioning
confidence: 99%
“…Bexarotene applied locally or in form of gel has shown results in the treatment of T cell lymphoma, acquired immunodeficiency Kaposi-sarcoma and one case diffuse large B-cell of the scalp (11)(12)(13)(14). Systemic chemotherapy including doxorubicin, cyclophospahmide, vincristine and prednisone as monotherapy or in combination as protocol COP (cyclophospahmide, vincristine and prednisone) or CHOP (doxorubicin, cyclophospahmide, vincristine and prednisone) achieved response in 98% but relapse rate was 33% (3,12,15). A multicenter prospective clinical study of 49 PCNHL patients with combination chemotherapy reported event-free survival of 50% at 5 years after treatment (16).…”
Section: Discussionmentioning
confidence: 99%
“…Most often “B” symptoms (night sweats, fever, and unintentional weight loss) are not noticed until the advanced stage of lymphoma [ 24 , 28 , 31 , 37 , 41 , 58 , 63 , 70 , 76 , 80 , 92 , 96 , 101 , 102 , 107 , 111 , 112 , 117 , 143 ]. Lymphadenopathy may be present and it is essential to carefully examine the lymph nodes of the palpable areas [ 2 , 13 , 20 , 21 , 24 , 28 , 30 , 33 , 34 , 37 , 42 , 43 , 48 , 49 , 52 , 53 , 57 , 58 , 62 , 63 , 66 , 70 , 71 , 72 , 73 , 74 , 76 , 77 , 84 , 86 , 89 , 92 , 94 , …”
Section: Diagnosismentioning
confidence: 99%
“…Lymphadenopathy may be present and it is essential to carefully examine the lymph nodes of the palpable areas [ 2 , 13 , 20 , 21 , 24 , 28 , 30 , 33 , 34 , 37 , 42 , 43 , 48 , 49 , 52 , 53 , 57 , 58 , 62 , 63 , 66 , 70 , 71 , 72 , 73 , 74 , 76 , 77 , 84 , 86 , 89 , 92 , 94 , 97 , 99 , 102 , 103 , 104 , 109 , 114 , 116 , 118 , 119 , 135 , 138 , 143 , 145 , 146 , 147 ]. Laboratory test results are also within normal limits in the early stages of the disease [ 6 , 19 , 24 , 28 ...…”
Section: Diagnosismentioning
confidence: 99%
“……”
Section: Combination Therapymentioning
confidence: 99%
