Topical silver for treating infected wounds

A Randomized Controlled Trial on the Outcome in Comparing an Alginate Silver Dressing With a Conventional Treatment of a Necrotizing Fasciitis Wound

“…As in previous large review studies, the trend of time for wound bed preparation and wound healing has favored Ag-containing dressing material groups. 18,19 However, our study did not show a statistical significance between the NSS group and the Ag group. 21-23 In addition, the shorter duration of wound bed preparation bring about shorter duration of hospital stay and reduced cost of treatment per case.…”

A Randomized Controlled Trial on the Outcome in Comparing an Alginate Silver Dressing With a Conventional Treatment of a Necrotizing Fasciitis Wound

“…As in previous large review studies, the trend of time for wound bed preparation and wound healing has favored Ag-containing dressing material groups. 18,19 However, our study did not show a statistical significance between the NSS group and the Ag group. 21-23 In addition, the shorter duration of wound bed preparation bring about shorter duration of hospital stay and reduced cost of treatment per case.…”

Silver dressings for the healing of venous leg ulcer

“…Previous systematic reviews and meta-analyses have not always supported the role of silver-containing dressings in the management of chronic wounds. [ 15 , 31 , 32 ] However, consistent with the current results, several studies have proved that silver dressings have great advantages in accelerating wound healing and reducing wound area in certain circumstances; [ 16 , 17 , 33 , 34 ] even so, few RCTs have found statistical differences in complete wound healing due to the lack of high-quality long-term follow-up clinical data. Carter et als study, [ 16 ] which included not only VLUs, but also other types of leg wounds, showing that silver treatments and silver dressings can significantly reduce the size of the wounds.…”

A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimicrobial solutions and wound dressings

“…The model allows for direct testing of antimicrobial solutions and wound dressings on mature 48‐h two‐species biofilm for up to 48 h. The layered CWB model exhibits microbiological resilience against antimicrobial solutions and wound dressings, which might give industry and clinicians a better indication of the clinical antibiofilm performance of such treatments. The observed relatively low antibiofilm effect of antimicrobial dressings containing silver and honey in the new in vitro model seems to be in better accordance with the relatively low level of clinical evidence for superiority of antimicrobial dressings and solutions in the treatment of chronically infected wounds 13,15,40,41 …”

A Randomized Controlled Trial on the Outcome in Comparing an Alginate Silver Dressing With a Conventional Treatment of a Necrotizing Fasciitis Wound

“…As in previous large review studies, the trend of time for wound bed preparation and wound healing has favored Ag-containing dressing material groups. 18,19 However, our study did not show a statistical significance between the NSS group and the Ag group. 21-23 In addition, the shorter duration of wound bed preparation bring about shorter duration of hospital stay and reduced cost of treatment per case.…”

Silver dressings for the healing of venous leg ulcer

“…Previous systematic reviews and meta-analyses have not always supported the role of silver-containing dressings in the management of chronic wounds. [ 15 , 31 , 32 ] However, consistent with the current results, several studies have proved that silver dressings have great advantages in accelerating wound healing and reducing wound area in certain circumstances; [ 16 , 17 , 33 , 34 ] even so, few RCTs have found statistical differences in complete wound healing due to the lack of high-quality long-term follow-up clinical data. Carter et als study, [ 16 ] which included not only VLUs, but also other types of leg wounds, showing that silver treatments and silver dressings can significantly reduce the size of the wounds.…”

A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimicrobial solutions and wound dressings

“…The model allows for direct testing of antimicrobial solutions and wound dressings on mature 48‐h two‐species biofilm for up to 48 h. The layered CWB model exhibits microbiological resilience against antimicrobial solutions and wound dressings, which might give industry and clinicians a better indication of the clinical antibiofilm performance of such treatments. The observed relatively low antibiofilm effect of antimicrobial dressings containing silver and honey in the new in vitro model seems to be in better accordance with the relatively low level of clinical evidence for superiority of antimicrobial dressings and solutions in the treatment of chronically infected wounds 13,15,40,41 …”

A Randomized Controlled Trial on the Outcome in Comparing an Alginate Silver Dressing With a Conventional Treatment of a Necrotizing Fasciitis Wound

“…As in previous large review studies, the trend of time for wound bed preparation and wound healing has favored Ag-containing dressing material groups. 18,19 However, our study did not show a statistical significance between the NSS group and the Ag group. 21-23 In addition, the shorter duration of wound bed preparation bring about shorter duration of hospital stay and reduced cost of treatment per case.…”

Silver dressings for the healing of venous leg ulcer

“…Previous systematic reviews and meta-analyses have not always supported the role of silver-containing dressings in the management of chronic wounds. [ 15 , 31 , 32 ] However, consistent with the current results, several studies have proved that silver dressings have great advantages in accelerating wound healing and reducing wound area in certain circumstances; [ 16 , 17 , 33 , 34 ] even so, few RCTs have found statistical differences in complete wound healing due to the lack of high-quality long-term follow-up clinical data. Carter et als study, [ 16 ] which included not only VLUs, but also other types of leg wounds, showing that silver treatments and silver dressings can significantly reduce the size of the wounds.…”

A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of antimicrobial solutions and wound dressings

“…The model allows for direct testing of antimicrobial solutions and wound dressings on mature 48‐h two‐species biofilm for up to 48 h. The layered CWB model exhibits microbiological resilience against antimicrobial solutions and wound dressings, which might give industry and clinicians a better indication of the clinical antibiofilm performance of such treatments. The observed relatively low antibiofilm effect of antimicrobial dressings containing silver and honey in the new in vitro model seems to be in better accordance with the relatively low level of clinical evidence for superiority of antimicrobial dressings and solutions in the treatment of chronically infected wounds 13,15,40,41 …”