Topical mupirocin treatment of impetigo is equal to oral erythromycin therapy

Topical Antibiotic Trends from 1993 to 2007: Use of Topical Antibiotics for Non-Evidence-Based Indications

“…In treatment of impetigo, topical antibiotics are a preferred first‐line therapy and can be more effective than systemic antibiotics 19 . Mupirocin specifically has been compared with oral erythromycin and oral cephalexin and was more effective for impetigo treatment in both cases 20,21 . Of greater significance is that much of the topical antibiotic use identified in our analysis may not be appropriate.…”

Topical Antibiotic Treatment of Impetigo with Tetracycline

“…Therefore, these outcomes suggest that topical tetracycline treatment is effective in the treatment of impetigo, although oral antibiotic treatment has long been the first choice for the treatment of this disease (1). In recent years, however, the resistance of staphylococci to oral antibiotics has increased dramatically (2, 6, 7, 18, 19).…”

“…In contrast, topical mupirocin has been shown to yield results equal to or even better than those of oral treatment (6, 7, 21, 23), although other authors have recommended that mupirocin be reserved for treatment of nasal carriage of S. aureus (10, 11).…”

“…Topical antibiotic treatment with mupirocin or fusidic acid has been shown to yield results equal to or even better than oral treatment (6–9). Some authors have recommended that mupirocin should be reserved for nasal carriage of Staphylococcus aureus in specific groups of patients (10, 11).…”

Evaluation of the effect of topical cefadroxil on bacterial load of pathogenic staphylococci in anterior nares in human volunteers, comparative study between oral vs. topical cefadroxil

“…[8][9][10][11][12][13][14][15][16] Aim of the Study On the basis of above mentioned data our aim of the study was to see whether its topical preparation has such efficacy or not. …”