Topical minoxidil therapy and hair regrowth

Topical Minoxidil Useful in 18% of Patients with Androgenetic Alopecia: A Study of 430 Cases

“…However, the mechanism of minoxidilinduced hypertrichosis is still unknown [5] and the recent suggestion that a metabolite of the drug is the active molecule might ex plain the variability in the results, depending on the patient's capacity to metabolize the drug [8].…”

“…However, opinions regarding the use and the effects of this treatment arc still con trasting [1][2][3][4][5].…”

Minoxidil Induces Selective Regrowth of Androgenetic Dependent Hair

“…It may cause reversible hypertrichosis if administered systemically. Topical application may lead to hair regrowth in alope cia areata and in androgenetic alopecia [1][2][3][4][5]. Mecha nisms of its action are still hypothetical.…”

“…Mecha nisms of its action are still hypothetical. Minoxidil may enhance cutaneous blood flow in the human balding scalp [5] and act as an immunomodulator [4]. System ic action may be evoked since hair regrowth may occur at sites distant to those treated [2].…”

“…System ic action may be evoked since hair regrowth may occur at sites distant to those treated [2]. Endocrinologic ef fects have not been demonstrated [4,5].…”