Topical Corticosteroids and Aqueous Humor Dynamics

Adrenocortical Hormones and Glaucoma

“…The pressure rise started already within 2 to 6 hours (20,22). An increase in aqueous flow was confirmed by Nicholas in normal and glaucomatous eyes (26). The treatment with corticosteroids (dexamethasone) in this study was extended over 3-6 weeks.…”

Adrenocortical Hormones and Glaucoma

“…The pressure rise started already within 2 to 6 hours (20,22). An increase in aqueous flow was confirmed by Nicholas in normal and glaucomatous eyes (26). The treatment with corticosteroids (dexamethasone) in this study was extended over 3-6 weeks.…”

In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model

“…The measured values of CDEX and CCON can then be used to calculate RDEX∗. Alternatively, if it is assumed that the difference between aqueous humor inflow and pressure-independent outflow is not affected by DEX treatment, i.e., that the major effect of DEX is simply to alter conventional outflow facility (54–57), then the C terms can be replaced byCDEXCCON=IOPCON−EVPIOPDEX−EVP.…”

Systemic Steroids and Ocular Fluid Dynamics. Ii

“…Generally, a decrease in outflow facility related to an increase in pressure has been found after topical application of steroids (Armaly 1965, 1966a, Becker 1965. Several observers (Linnkr 1959, Nicholas 1964, Draeger 1965, however, have noted that in a significant proportion of individuals an adequate reduction in outflow facility was not shown. In order to analyse the behaviour of our group in this respect, the sample was divided into 2 groups according to the level of pressure rise following topical dexamethasone.…”

Adrenocortical Hormones and Glaucoma

“…The pressure rise started already within 2 to 6 hours (20,22). An increase in aqueous flow was confirmed by Nicholas in normal and glaucomatous eyes (26). The treatment with corticosteroids (dexamethasone) in this study was extended over 3-6 weeks.…”

In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model

“…The measured values of CDEX and CCON can then be used to calculate RDEX∗. Alternatively, if it is assumed that the difference between aqueous humor inflow and pressure-independent outflow is not affected by DEX treatment, i.e., that the major effect of DEX is simply to alter conventional outflow facility (54–57), then the C terms can be replaced byCDEXCCON=IOPCON−EVPIOPDEX−EVP.…”

Systemic Steroids and Ocular Fluid Dynamics. Ii

“…Generally, a decrease in outflow facility related to an increase in pressure has been found after topical application of steroids (Armaly 1965, 1966a, Becker 1965. Several observers (Linnkr 1959, Nicholas 1964, Draeger 1965, however, have noted that in a significant proportion of individuals an adequate reduction in outflow facility was not shown. In order to analyse the behaviour of our group in this respect, the sample was divided into 2 groups according to the level of pressure rise following topical dexamethasone.…”

Adrenocortical Hormones and Glaucoma

“…The pressure rise started already within 2 to 6 hours (20,22). An increase in aqueous flow was confirmed by Nicholas in normal and glaucomatous eyes (26). The treatment with corticosteroids (dexamethasone) in this study was extended over 3-6 weeks.…”

In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model

“…The measured values of CDEX and CCON can then be used to calculate RDEX∗. Alternatively, if it is assumed that the difference between aqueous humor inflow and pressure-independent outflow is not affected by DEX treatment, i.e., that the major effect of DEX is simply to alter conventional outflow facility (54–57), then the C terms can be replaced byCDEXCCON=IOPCON−EVPIOPDEX−EVP.…”

Systemic Steroids and Ocular Fluid Dynamics. Ii

“…Generally, a decrease in outflow facility related to an increase in pressure has been found after topical application of steroids (Armaly 1965, 1966a, Becker 1965. Several observers (Linnkr 1959, Nicholas 1964, Draeger 1965, however, have noted that in a significant proportion of individuals an adequate reduction in outflow facility was not shown. In order to analyse the behaviour of our group in this respect, the sample was divided into 2 groups according to the level of pressure rise following topical dexamethasone.…”