Dear Editor, A rare, highly contagious viral infection known as "tomato flu" is spreading among children in India [1,2]. After the first patient was diagnosed in May 2022 in the southern state of Kerala, tomato flu has been reported in over 100 young children by August in Kerala, Tamil Nadu, Odisha, and Haryana [3]. The emergence of increasing cases in the initial phases has raised concerns regarding the rapidity of its spread. According to experts, young children are most vulnerable to this illness because their immune systems are underdeveloped, making them more prone to becoming infected, but it does not easily pass on to adults [4].Another possible factor contributing to the increase in infection among young children is the reopening of schools following their closure during the COVID-19 pandemic. It is seen that children in the age group of 1-9 years are mostly affected by the outbreak. Though children as old as 9 years have been affected, it is reported that the virus is mostly seen in children under-5 years. In the United Kingdom, the first cases described were that of a 5 year boy and his infant sister (13 months). They had rashes on their hands and legs 1 week after returning from a family vacation in Kerala, India. They denied interacting with sick children, despite having played with another child who had recently recovered from "tomato flu" like symptoms [3,4].Instances similar to tomato fever were previously recorded in 2007 in Kerala, when many people were affected in Varzur, Mudakayam, and Kanirapally in Kottayam and Pathinamtita districts, where chikungunya was also reported at the same time. However, the increasing cases of tomato flu have now become a concern as it is found to affect more children under five than usual [1]. Tomato flu infection is believed to be a variant of the viral hand-foot-and-mouth disease (HFMD), a common condition primarily affecting children aged 1-5 years [2]. According to the Centers for Disease Control and Prevention, HFMD is a highly contagious disease caused by the coxsackievirus (CA16) and spreads quickly through an infected person's nasal and throat secretions, excrements, and fluid from blisters. Fever and flu-like symptoms, oral sores, and skin rash are common symptoms. The CA16 is one of India's most common enteroviruses and one should not expect this infection to be found limited to a single geographic region [5].This viral infection is known as tomato flu because the symptoms include little grapelike blisters that can grow as large as a tomato and are red like a tomato. It has nothing to do with tomatoes or the use of tomatoes. The primary symptoms in children include fever, sores in the mouth, a skin rash, fatigue, vomiting, nausea, dehydration, body aches, intense joint pain, and diarrhea. Traditionally, tomato flu rashes were limited to the mouth (tongue, gums, and inside of the cheek), palms, and soles. However, clinicians are now reporting rashes on the buttocks and peeling of the nails. The tomato flu is a nonlife threatening viral infection with sympt...