Toluene [MAK Value Documentation, 1996]

doi:10.1002/3527600418.mb10888e0007

The MAK‐Collection for Occupational Health and Safety 2012

DOI: 10.1002/3527600418.mb10888e0007

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Toluene [MAK Value Documentation, 1996]

Abstract: Published in the series Occupational Toxicants , Vol. 7 (1996) The article contains sections titled: Recent Reviews Toxic Effects and Modes of Action Uptake, Biotransformation and Excretion Effects in Man Single exposures Repeated exposures … Show more

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References 155 publications

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Toluene, ethylbenzene and phenol – Determination of o‐cresol, m‐cresol, 2‐ethylphenol, 4‐ethylphenol and phenol in urine using gas chromatography‐mass spectrometry [Biomonitoring Methods, 2011]

Schettgen

Alt

Dewes

2017

The MAK‐Collection for Occupational Health and Safety

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The article contains sections titled: General principles Equipment, chemicals and solutions Equipment Chemicals Solutions Internal standard Calibration standards Specimen collection and sample preparation Sample preparation for the determination of cresols and ethylphenols Sample preparation for the determination of phenol Operational parameters Gas chromatography Mass spectrometry Analytical determination Calibration Calculation of the analytical results Standardisation and quality control Evaluation of the method Precision Accuracy Absolute recovery Detection limits and quantitation limits Sources of error Discussion of the method

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Toluene, ethylbenzene and phenol – Determination of o‐cresol, m‐cresol, 2‐ethylphenol, 4‐ethylphenol and phenol in urine using gas chromatography‐mass spectrometry [Biomonitoring Methods, 2011]

Schettgen

Alt

Dewes

2017

The MAK‐Collection for Occupational Health and Safety

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Aromatic Compounds in Blood – Determination using Headspace Gas Chromatography with Mass Spectrometric Detection [Biomonitoring Methods, 2018]

Hartwig¹,

Arand²

2018

The MAK‐Collection for Occupational Health and Safety

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The working group „Analyses in Biological Materials“ of the Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area verified the presented biomonitoring method. The here described analytical method enables the simultaneous determination of benzene, toluene, chlorobenzene, ethylbenzene, o‐xylene, m‐xylene, p‐xylene, styrene, n‐propylbenzene, isopropylbenzene (cumene), 1,2,3‐trimethylbenzene (hemimellitene), 1,2,4‐trimethylbenzene, 1,3,5‐trimethylbenzene (mesitylene) and 1,2,3,5‐tetramethylbenzene (isodurene) in blood. For determination, the blood samples are introduced into headspace vials. The vials are sealed and heated to 50 °C in the autosampler. Subsequently, an aliquot of the vapour phase is injected into the GC system and analysed using mass spectrometry. Calibration standards are prepared in ovine blood and processed in the same way as the samples to be analysed.

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Toluene [MAK Value Documentation, 1996]

Abstract: Published in the series Occupational Toxicants , Vol. 7 (1996) The article contains sections titled: Recent Reviews Toxic Effects and Modes of Action Uptake, Biotransformation and Excretion Effects in Man Single exposures Repeated exposures … Show more

Cited by 2 publications

References 155 publications

Toluene, ethylbenzene and phenol – Determination of o‐cresol, m‐cresol, 2‐ethylphenol, 4‐ethylphenol and phenol in urine using gas chromatography‐mass spectrometry [Biomonitoring Methods, 2011]

Toluene, ethylbenzene and phenol – Determination of o‐cresol, m‐cresol, 2‐ethylphenol, 4‐ethylphenol and phenol in urine using gas chromatography‐mass spectrometry [Biomonitoring Methods, 2011]

Aromatic Compounds in Blood – Determination using Headspace Gas Chromatography with Mass Spectrometric Detection [Biomonitoring Methods, 2018]

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