Toll-like receptor 2 subfamily genotypes are not associated with severity of bronchiolitis or postbronchiolitis wheezing in infants

Abstract

TLR2 subfamily gene polymorphisms were not associated with severity of bronchiolitis or risk of postbronchiolitis wheezing.

Toll‐like receptor‐1, ‐2, and ‐6 genotypes in relation to salivary human beta‐defensin‐1, ‐2, ‐3 and human neutrophilic peptide‐1

“…Genotype frequencies of TLR1 (wild type 67.8%), TLR2 (wild type 95.5%), and TLR6 (wild type 28.7%) were almost identical to the frequencies reported in another Finnish population study (TLR1 wild type 70%, TLR2 wild type 95%, and TLR6 wild type 28.7%) (Nuolivirta et al, 2013). Genotype variations between populations have been previously described for TLR1 (rs5743618) (Barreiro et al, 2009).…”

Toll‐like receptor‐1, ‐2, and ‐6 genotypes in relation to salivary human beta‐defensin‐1, ‐2, ‐3 and human neutrophilic peptide‐1

“…Genotype frequencies of TLR1 (wild type 67.8%), TLR2 (wild type 95.5%), and TLR6 (wild type 28.7%) were almost identical to the frequencies reported in another Finnish population study (TLR1 wild type 70%, TLR2 wild type 95%, and TLR6 wild type 28.7%) (Nuolivirta et al, 2013). Genotype variations between populations have been previously described for TLR1 (rs5743618) (Barreiro et al, 2009).…”

Toll‐like receptor 2 subfamily gene polymorphisms are associated with Bacillus Calmette‐Guérin osteitis following newborn vaccination

“…In addition, TLR1 T1805G has a very high population differentiation . The minor allele frequency of TLR1 is much lower in the Finnish population than in other European populations . In the present study, the minor allele frequency of TLR1 was lower in the cases than in the population‐based controls.…”

Association between single nucleotide polymorphisms in TLR4 , TLR2 , TLR9 , VDR , NOS2 and CCL5 genes with acute viral bronchiolitis

“…Additionally, TLR4 signaling was reported to influence TLR2 expression following certain stimuli, suggesting a role for both TLR4 and TLR2 in the response to RSV (Fan et al, 2003). One study found no association between TLR1, TLR2, and TLR6 polymorphisms and the bronchiolitis severity (Nuolivirta et al, 2013). We found that death in bronchiolitis is associated with SNP rs1898830 (TLR2) in patients without comorbidities.…”

Toll‐like receptor‐1, ‐2, and ‐6 genotypes in relation to salivary human beta‐defensin‐1, ‐2, ‐3 and human neutrophilic peptide‐1

“…Genotype frequencies of TLR1 (wild type 67.8%), TLR2 (wild type 95.5%), and TLR6 (wild type 28.7%) were almost identical to the frequencies reported in another Finnish population study (TLR1 wild type 70%, TLR2 wild type 95%, and TLR6 wild type 28.7%) (Nuolivirta et al, 2013). Genotype variations between populations have been previously described for TLR1 (rs5743618) (Barreiro et al, 2009).…”

Toll‐like receptor 2 subfamily gene polymorphisms are associated with Bacillus Calmette‐Guérin osteitis following newborn vaccination

“…In addition, TLR1 T1805G has a very high population differentiation . The minor allele frequency of TLR1 is much lower in the Finnish population than in other European populations . In the present study, the minor allele frequency of TLR1 was lower in the cases than in the population‐based controls.…”

Association between single nucleotide polymorphisms in TLR4 , TLR2 , TLR9 , VDR , NOS2 and CCL5 genes with acute viral bronchiolitis

“…Additionally, TLR4 signaling was reported to influence TLR2 expression following certain stimuli, suggesting a role for both TLR4 and TLR2 in the response to RSV (Fan et al, 2003). One study found no association between TLR1, TLR2, and TLR6 polymorphisms and the bronchiolitis severity (Nuolivirta et al, 2013). We found that death in bronchiolitis is associated with SNP rs1898830 (TLR2) in patients without comorbidities.…”

Toll‐like receptor‐1, ‐2, and ‐6 genotypes in relation to salivary human beta‐defensin‐1, ‐2, ‐3 and human neutrophilic peptide‐1

“…Genotype frequencies of TLR1 (wild type 67.8%), TLR2 (wild type 95.5%), and TLR6 (wild type 28.7%) were almost identical to the frequencies reported in another Finnish population study (TLR1 wild type 70%, TLR2 wild type 95%, and TLR6 wild type 28.7%) (Nuolivirta et al, 2013). Genotype variations between populations have been previously described for TLR1 (rs5743618) (Barreiro et al, 2009).…”

Toll‐like receptor 2 subfamily gene polymorphisms are associated with Bacillus Calmette‐Guérin osteitis following newborn vaccination

“…In addition, TLR1 T1805G has a very high population differentiation . The minor allele frequency of TLR1 is much lower in the Finnish population than in other European populations . In the present study, the minor allele frequency of TLR1 was lower in the cases than in the population‐based controls.…”

Association between single nucleotide polymorphisms in TLR4 , TLR2 , TLR9 , VDR , NOS2 and CCL5 genes with acute viral bronchiolitis

“…Additionally, TLR4 signaling was reported to influence TLR2 expression following certain stimuli, suggesting a role for both TLR4 and TLR2 in the response to RSV (Fan et al, 2003). One study found no association between TLR1, TLR2, and TLR6 polymorphisms and the bronchiolitis severity (Nuolivirta et al, 2013). We found that death in bronchiolitis is associated with SNP rs1898830 (TLR2) in patients without comorbidities.…”