To study hematological profile in malaria patients

Yadav, Rakesh Kumar; Kumar, Sujit

doi:10.18203/2349-3933.ijam20172132

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…In studies like Yadav RK et al, and Surve KM et al, had similar rates of male: female ratio which is 1.32:1 in both. 7,8 In other studies like Khuraiya P et al, and Patel G et al 9,10 also some near similar rates above studies which are 1.26: 1 and 1.30:1 respectively. Some studies showed very high incidence in males compared to females like Kalavati GP et al, showed a very high male incidence which is more than three times that of the female which is 3.38:1.…”

Section: Discussionsupporting

confidence: 67%

Clinical profile of falciparum, vivax and mixed infections of malaria, from a tertiary care hospital, Coastal Andhra, India

et al. 2020

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Background: Malaria is a major health problem in many parts of India and some parts of Andhra Pradesh is one of the endemic areas for malaria. The objective was to study clinical profile and outcome of malaria in both species and mixed infection.Methods: Present study was carried out on 100 patients admitted during the period of November 2016 - October 2018 in Narayana medical college and hospital, Nellore. Malaria confirmed by Peripheral thick and thin smear or Antigen Assay underwent detailed clinical history and physical examination. This was followed by monitoring the outcome of the patients with respect to morbidity and mortality.Results: Out Of the 100 patients 58 patients were from rural background, males were predominant, most common age group was 20-30 (34%) followed by 31-40 (31%). Out of 100 patients, 54 patients were falciparum,44 patients had vivax and two had mixed infection. All of the patients had fever followed by chills and rigors (75%), nausea and vomiting (59%), easy fatiguability (28%), pain abdomen (17), cough (14%) in both infections, altered sensorium was seen in only falciparum (20.3%). On clinical examination,70% of the patients had pallor, splenomegaly in 46%, icterus (23%), hepatomegaly (14%) and pedal edema in12 patients were observed. All 0f the patients were treated with appropriate antimalarial drugs for appropriate duration, and all were recovered without any mortality.Conclusions:Malaria is very common disease in our country especially in South India, which is one of the endemic areas. Severe malaria usually caused by the falciparum more than vivax, early diagnosis and treatment decreases the mortality and morbidity.

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Section: Discussionsupporting

confidence: 67%

Clinical profile of falciparum, vivax and mixed infections of malaria, from a tertiary care hospital, Coastal Andhra, India

et al. 2020

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“…Some studies like Surve KM et al which had 79% and Yadav RK et al, study had 80% of anemia incidence in their studies both of which are similar to our present study. 9,10 But in other studies had very low incidence of malaria compared to this study. In Vaidya MS et al, study it was about 27.3%.…”

Section: Discussioncontrasting

confidence: 51%

Haematological profile and its outcome in different species of malaria: a two year study

et al. 2020

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Background: Malaria is a major health problem in many parts of India and some parts of Andhra Pradesh, which is also one of the endemic areas for malaria. Several factors have been attributed to increased morbidity and mortality in malaria especially with altered hematological and coagulation parameters playing an important role. The aim of present study was to study the hematological and coagulation abnormalities that correspond to severity and the final outcome.Methods: The present study was carried out on 100 patients admitted during the period of November 2016 to October 2018 at Narayana Medical College and hospital, Nellore. All of these patients were confirmed by Peripheral Smear or MPQBC or Antigen Assay followed by detailed clinical history, physical examination and investigated with hematological and coagulation parameters. Then subsequently required routine and special investigation which was followed by monitoring the outcome of the patients with respect to morbidity and mortality.Results: Out of 100 patients 20 patients had severe anemia (Hb% <7 gm%) and most of them patients were falciparum and mixed infection cases. Thrombocytopenia was observed in 63% of the patients and severe thrombocytopenia (<50,000 mm3) was seen in 12% of the patients. PT and APTT were increased in 18% and 13% of the cases respectively. BT was increased in 5% of the cases. None of the patients expired in this study.Conclusions: severe anemia is a poor prognostic factor and has adverse outcome. Thrombocytopenia, increased PT, APTT does not have any correlation to mortality.

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“…The cases of P. vivax included 45 men and 15 females, while the cases of P. falciparum were 18 males and 22 females. The investigations conducted by Yadav RK et al [17] and Surve KM et al [18] reported a male to female ratio of 1.32:1, indicating comparable rates. Fever was the predominant manifestation in all 100 individuals, regardless of whether they were infected with falciparum or vivax.…”

Section: Discussionmentioning

confidence: 78%

A hospital-based study to compare the clinical profile of P. falciparum, P. vivax and mixed infections of malaria: Retrospective study

Babu,

Srinivas,

Thatikonda

et al. 2023

Int. J. Mosq. Res.

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The objective of this study was to compare the clinical profile of P. falciparum, P. vivax and mixed infections of malaria. Methods: This retrospective observational study included malaria patients who were admitted to a tertiary care teaching hospital. Inpatient retrieved and scrutinized on the basis of the patient's demographic profile, clinical findings, investigations, treatment, and complications during this 12-month period. The institutional ethical committee approved the study. A total of 100 subjects were included. Results:The study included a total of 60 cases of P. vivax and 40 cases of P. falciparum. The cases of P. vivax included 45 men and 15 females, while the cases of P. falciparum were 18 males and 22 females. Fever was the predominant manifestation in all 100 individuals, regardless of whether they were infected with falciparum or vivax. Subsequently, 80 individuals had chills and rigours, with 45 of them having falciparum infection and 35 of them infected with vivax. Among the total patients, 70% reported experiencing nausea and vomiting, with a higher prevalence identified in those with falciparum malaria (40%) compared to those with vivax malaria (30%). Another less prevalent symptom was easy fatiguability, which was reported in 30 individuals, whereas cough was evident in 20 patients. These signs were more often found in falciparum malaria compared to vivax malaria. Altered consciousness was only found in 12 individuals with falciparum malaria. Patients with mixed infection had a wide range of symptoms including fever accompanied by chills and rigours, excessive fatigue, vomiting, coughing, and changes in mental alertness. The bivariate analysis of the clinical characteristics and consequences of P. vivax and P. falciparum malaria did not reveal any statistically significant difference. Conclusion: This study finding indicate that P. vivax mono infection has a comparable progression and consequences to malaria caused by P. falciparum mono infection.

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To study hematological profile in malaria patients

Cited by 4 publications

References 8 publications

Clinical profile of falciparum, vivax and mixed infections of malaria, from a tertiary care hospital, Coastal Andhra, India

Clinical profile of falciparum, vivax and mixed infections of malaria, from a tertiary care hospital, Coastal Andhra, India

Haematological profile and its outcome in different species of malaria: a two year study

A hospital-based study to compare the clinical profile of P. falciparum, P. vivax and mixed infections of malaria: Retrospective study

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