2004
DOI: 10.1001/jama.292.6.671
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To "E" or Not to "E," Vitamin E's Role in Health and Disease Is the Question

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“…Hepatic α-TPP has the greatest affinity for α-tocopherol compared to γ-tocopherol and is crucial for the relative percentage of transport of various vitamin E forms in plasma lipoproteins. High intake of α-tocopherol may reduce intestinal absorption, cell membrane transport, and utilization of other forms of tocopherols, especially γ-tocopherol [ 42 ]. Furthermore, γ-tocopherol intake was negatively associated with plasma α-tocopherol [ 9 ].…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Hepatic α-TPP has the greatest affinity for α-tocopherol compared to γ-tocopherol and is crucial for the relative percentage of transport of various vitamin E forms in plasma lipoproteins. High intake of α-tocopherol may reduce intestinal absorption, cell membrane transport, and utilization of other forms of tocopherols, especially γ-tocopherol [ 42 ]. Furthermore, γ-tocopherol intake was negatively associated with plasma α-tocopherol [ 9 ].…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Tocotrienols and tocopherols possess a common chemical structure of a chromonal ring and a side chain with the exception that the former has an unsaturated isoprenoid side chain when compared with the latter with a saturated phytyl tail. Studies have shown varying potencies of these isoforms on different biological functions (Burton and Ingold 1989;Komiyama and others 1989;Friderich 2004).…”
Section: Introductionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.