To compare and evaluate the antimicrobial activity of three different root canal sealers: An In Vitro Study

Abstract

Aim of the Study: The purpose of this study is to compare and analyze the antimicrobial activity of three different root canal sealers. Materials and Methods: In this study, the antimicrobial activity of three different root canal sealers were compared against two strains of bacteria Enterococcus faecalis which is known to be common isolates of necrotic pulp and endodontic lesions. This test was done at various time intervals (1, 6, 15, and 60 min) using agar diffusion test and direct contact test. Results: Bioceramic showed the best antimicrobial activity against E. faecalis among the three groups of sealers used. Moreover, the results were statistically analyzed. Conclusion: Within the limitations of this study, it can be concluded that Bioceramic sealer showed the best antimicrobial activity followed by MTA Fillapex and Apexit.

In vitro evaluation of the antibacterial effects of MTA- Fillapex and BIO-C® sealer at different time intervals

“…In one day and one weeks bioceramic sealer act in a better way, which may be due to the sealer containing an amount of oxide compounds that potentially have antimicrobial activity These findings are consistent with previous researches conducted on bioceramic sealers have significant antibacterial efficacy against E. faecalis up to one week (19,26,28,29) Also in another study, Mangat et al(29) compared the antimicrobial activity of Bioceramic BC sealer and MTA fillapex sealer against E. faecalis at distinct time intervals from 1day to 1 week and concluded that Bioceramic sealer showed better antimicrobial activity than MTA Fillapex and Apexit in both (ADT) and (DCT). In another word was implemented and Figure 2 depicts the antimicrobial activity of tested endodontic sealers made from a modified direct contact test.…”

Evaluation of minimum inhibitory concentration and minimum bactericidal concentration of royal jelly against Enterococcus faecalis, Staphylococcus aureus, and Candida albicans

“…[ 19 ] If RJ can effectively eliminate E. faecalis at a concentration of 10 mg/ml, it may hold promise as an adjunctive treatment in cases of persistent endodontic infections where E. faecalis is implicated. In the field of endodontics, where infections can involve various microorganisms,[ 20 21 ] having an antimicrobial agent effective against both bacteria and fungi such as C. albicans is highly advantageous.…”

To check the antibacterial efficacy against Enterococcus faecalis by various ayurvedic oils used as a solvent in endodontic sealers - An in vitro study

“…Root canal sealers with antimicrobial activity can help improve the success rate of endodontic treatment and are especially advantageous in clinical situations where there is a persistent or recurrent infection. [ 9 10 11 ]…”