Titration of Herpes Gestationis Factor Fixing to C3 in Pemphigoid Herpes Gestationis Associated With Choriocarcinoma

Herpes Gestationis after Ovodonation: Is Placenta the only Target of the Immune Reaction?

“…Accordingly, the patients frequently develop other autoimmune diseases such as Graves' disease [1]. Furthermore, a rare association with molar pregnancies [5] and choriocarcinoma [6] has been reported, stressing the possible causal role of paternal antigens as the target of anti-HLA antibodies that subsequently to cross-react with the skin.…”

Pruritus in Pregnancy

“…The first cases of PG complicating egg donation pregnancy have recently been reported [40,41]. Beyond pregnancy, it can very rarely occur in association with trophoblastic tumors (choriocarcinoma and hydatidiform mole) [42][43][44][45][46][47][48]. The incidence is approximately 1:2000-1:60,000 pregnancies, depending on the prevalence of the human leukocyte antigen (HLA) haplotypes DR3 and DR4 [49,50].…”

Treatment of Autoimmune Bullous Diseases During Pregnancy and Lactation: A Review Focusing on Pemphigus and Pemphigoid Gestationis

“…Although it usually resolves after delivery, it may also show a persistent or chronic-relapsing course, with flares usually occurring after delivery, during menses, or in association with the use of hormonal contraceptives. In cases associated with gestational trophoblastic disease, the treatment of underlying condition may facilitate PG remission ( Slazinski and Degefu, 1982 ; do Valle Chiossi et al, 2000 ; Djahansouzi et al, 2003 ). The treatment is non-standardized, with most evidence derived from individual case reports or small series, currently there being no specific guidelines.…”