2004
DOI: 10.1007/s10029-004-0292-8
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Abstract: Titanium and its alloys are used worldwide in surgery. The favorable characteristics that make this material desirable for implantation are corrosion resistance and biocompatibility. Concerning hernia repair, a mesh modification has been developed using titanium layering of a polypropylene mesh implant, which is said to lead to an improved biocompatibility compared to commercially available mesh materials. To analyze the pure effect of titanium coating, two different mesh structures were studied using a standa… Show more

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Cited by 49 publications
(29 citation statements)
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“…In our rat model, no differences were found between tPPM, PPM, and PGM in terms of proliferation, apoptosis, or the percentage volume of inflammatory cells in the tissue (%PV), neither in the semisterile nor in the bacterial contamination arm, nor the clinical parameters (wound infection rate, peritonitis, and adhesion score) did any differences between the individual materials reveal. This is in accordance with the results of the experiments of Junge et al [10], where no beneficial effect of titanium coating of propylene meshes was reported in a rat model. In the bacterial contamination arm, abscess-generating mesh infection was observed with all the materials used.…”
Section: Discussionsupporting
confidence: 92%
“…In our rat model, no differences were found between tPPM, PPM, and PGM in terms of proliferation, apoptosis, or the percentage volume of inflammatory cells in the tissue (%PV), neither in the semisterile nor in the bacterial contamination arm, nor the clinical parameters (wound infection rate, peritonitis, and adhesion score) did any differences between the individual materials reveal. This is in accordance with the results of the experiments of Junge et al [10], where no beneficial effect of titanium coating of propylene meshes was reported in a rat model. In the bacterial contamination arm, abscess-generating mesh infection was observed with all the materials used.…”
Section: Discussionsupporting
confidence: 92%
“…However, there were no significant differences in inflammatory cell infiltration or proliferation. In a similar study, Junge et al compared the tissue inflammatory response between two lightweight PP meshes, one coated with titanium and the other without [50]. The tissues were assessed at 56, 84, and 182 days postimplantation.…”
Section: Coated Pp Meshesmentioning
confidence: 99%
“…2 However, Junge et al, found significant less inflammation in PP-mesh compared with the Ti-coated PP-mesh after implantations of 84 and 182 days in rats. 27 If a medical implant gets infected, it may have drastic consequences such as the need for reoperation and removal of it. Implant infection can result in life-threatening sepsis.…”
Section: Discussionmentioning
confidence: 99%