Titanium-Biohybrid Middle Ear Prostheses: A Preliminary In Vitro Study
Mario Mosconi,
Elena Carlotto,
Laura Caliogna
et al.
Abstract:Tissue bioengineering has been assuming a pivotal role in implementing alternatives to conven-tional ossicular middle ear replacement prostheses to overcome extrusion while preserving acoustic properties. This in vitro study aims to explore for the first time in current literature the feasibility of a biohybrid middle ear prosthesis composed of titanium surrounded by bone ex-tracellular matrix as bio-coating. We have hereby studied the adhesion and proliferation of human adipose-derived mesenchymal stem cells … Show more
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