2005
DOI: 10.1007/s00432-005-0066-4
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Abstract: "Morphologically normal tissues" adjacent to carcinomas present abnormal t-PA activity that is associated with the degree of tumor progression. Assaying of this activity could be useful as a predictive parameter.

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Cited by 3 publications
(2 citation statements)
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References 41 publications
(83 reference statements)
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“…However, Vidal et al showed that the preoperative serum uPA levels in gastric cancer patients were similar to those in the control subjects . High expression of uPAR, uPA, and PAI‐1 was observed in gastric tumors compared to normal tissues . Further, the expression of uPA and uPAR in gastric cancer was correlated to poor outcome .…”
Section: Clinical Relevance Of Components Of Upa System In Human Cancersmentioning
confidence: 99%
“…However, Vidal et al showed that the preoperative serum uPA levels in gastric cancer patients were similar to those in the control subjects . High expression of uPAR, uPA, and PAI‐1 was observed in gastric tumors compared to normal tissues . Further, the expression of uPA and uPAR in gastric cancer was correlated to poor outcome .…”
Section: Clinical Relevance Of Components Of Upa System In Human Cancersmentioning
confidence: 99%
“…Tissue plasminogen activator (tPA) is the intra-vascular counterpart to uPA, involved in fibrin degradation to prevent blood clot formation [13]. However, tPA does not appear to play a significant role in the development of solid tumours [16].…”
Section: Introductionmentioning
confidence: 99%