Tissue specific responses of oysters, Crassostrea virginica, to silver nanoparticles

Tissue specific responses to cadmium-based quantum dots in the marine mussel Mytilus galloprovincialis

“…Recent studies suggest that the gills are more susceptible to dissolved metal toxicity, while digestive gland is more sensitive to ENPs (McCarthy et al, 2013;Gomes et al, 2012). Higher ENP concentrations were found in the digestive gland compared to gills from bivalves exposed to different ENPs, such as fullerenes, Au NPs, Ag NPs, CuO NPs and CdTe QDs (Tedesco et al, 2010;Al-Subiai et al, 2012;Gomes et al, 2012;McCarthy et al, 2013;Rocha et al, 2015a). This differential tissue accumulation was related to highly developed processes for the cellular internalization of nano-and microscale particles (endocytosis and phagocytosis) in the digestive gland cells (Moore et al, 2006;Canesi et al, 2012), nevertheless it has been demonstrated that gills can also be a main target for ENPs (Koehler et al, 2008;Trevisan et al, 2014).…”

“…These tissue-specific responses were previously reported in bivalves exposed to other ENPs, such as Ag NPs in mussels M. galloprovincialis (42 ± 9.6 nm; 10 µg.L -1 ; 15 d) and in oysters C. virginica (20-30 nm; 0.02-20 mg.L -1 ; 48 h) (McCarthy et al, 2013), indicating differential biophysicochemical interactions at the interfaces between metal-based ENPs and marine organisms when compared to its dissolved counterparts.…”

Cellular responses of eastern oysters, Crassostrea virginica, to titanium dioxide nanoparticles

“…Increases in lysosomal destabilization and lipid 508 peroxidation were observed in oysters exposed to AgNPs at concentrations as low as 0.2 509 -and 2 µg/L (McCarthy et al 2013). Lysosomal destabilization was significantly 510 affected at 50 µg/L for TiO 2 -NPs, and 10 µg/L for fullerenes (Ringwood et al, 2009), but 511…”

Comparative antioxidant status in freshwater fish Carassius auratus exposed to eight imidazolium bromide ionic liquids: A combined experimental and theoretical study

“…GSH is the most abundant cellular antioxidant, and maintenance of baseline levels is essential for cellular homeostasis and resisting toxicity from oxidative stress (McCarthy et al, 2013). On one hand, GSH can interact directly with some ROS for their detoxification.…”