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Cited by 3 publications
(1 citation statement)
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“…TRIM24 expression is aberrantly up-regulated in many cancers, including breast cancer, where overexpression correlates with poor survival of patients (7,(12)(13)(14). Using an immortalized human mammary epithelial cell culture model, we previously reported oncogenic function of TRIM24 in promoting malignant transformation in vitro and xenograft tumor forma-tion in vivo (15,16). Although many reports have correlated TRIM24 overexpression with multiple cancers, the basic mechanisms of how TRIM24 functions, especially with regard to regulation of TRIM24 itself, are not well understood.…”
Section: Proteins With Domains That Recognize and Bind Post-translatimentioning
confidence: 99%
“…TRIM24 expression is aberrantly up-regulated in many cancers, including breast cancer, where overexpression correlates with poor survival of patients (7,(12)(13)(14). Using an immortalized human mammary epithelial cell culture model, we previously reported oncogenic function of TRIM24 in promoting malignant transformation in vitro and xenograft tumor forma-tion in vivo (15,16). Although many reports have correlated TRIM24 overexpression with multiple cancers, the basic mechanisms of how TRIM24 functions, especially with regard to regulation of TRIM24 itself, are not well understood.…”
Section: Proteins With Domains That Recognize and Bind Post-translatimentioning
confidence: 99%