Tissue engineering; strategies, tissues, and biomaterials

Bakhshandeh, Behnaz; Zarrintaj, Payam; Oftadeh, Omid; Keramati, Farid; Fouladiha, Hamideh; Sohrabi-Jahromi, Salma; Ziraksaz, Zarrintaj

doi:10.1080/02648725.2018.1430464

Cited by 154 publications

(92 citation statements)

References 220 publications

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“…It constitutes a protective barrier towards outer world, and thus is susceptible to damage resulting from inter alia burns, surgical procedures, or diabetic ulcers. To enhance wound repair and regeneration, many tissue-engineered skin products have been developed [232][233][234][235][236]. In general, biomaterials for treatment of skin injuries can be divided on two groups including wound dressings and skin substitutes ( Table 1).…”

Section: Skin Tementioning

confidence: 99%

“…In other words, they should have optimal water vapor transmission ratio (WVTR) and great ability to absorb wound exudate (if it occurs). Moreover, modern wound dressings should also accelerate wound healing [232][233][234]236,[242][243][244][245]. Progress in the field of engineering of biomaterials has led to the development of many promising wound dressings.…”

Section: Hacat and Bj Cell Lines/ Micementioning

confidence: 99%

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Proteins and Peptides as Important Modifiers of the Polymer Scaffolds for Tissue Engineering Applications—A Review

2020

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Polymer scaffolds constitute a very interesting strategy for tissue engineering. Even though they are generally non-toxic, in some cases, they may not provide suitable support for cell adhesion, proliferation, and differentiation, which decelerates tissue regeneration. To improve biological properties, scaffolds are frequently enriched with bioactive molecules, inter alia extracellular matrix proteins, adhesive peptides, growth factors, hormones, and cytokines. Although there are many papers describing synthesis and properties of polymer scaffolds enriched with proteins or peptides, few reviews comprehensively summarize these bioactive molecules. Thus, this review presents the current knowledge about the most important proteins and peptides used for modification of polymer scaffolds for tissue engineering. This paper also describes the influence of addition of proteins and peptides on physicochemical, mechanical, and biological properties of polymer scaffolds. Moreover, this article sums up the major applications of some biodegradable natural and synthetic polymer scaffolds modified with proteins and peptides, which have been developed within the past five years.

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Section: Skin Tementioning

confidence: 99%

Section: Hacat and Bj Cell Lines/ Micementioning

confidence: 99%

Proteins and Peptides as Important Modifiers of the Polymer Scaffolds for Tissue Engineering Applications—A Review

2020

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“…Architected scaffolds should exhibit the proper biocompatibility, cell proliferation, growth, adhesion, and differentiation. Designed scaffolds should also possess the high interconnected porosity with enormous specific surface area to provide the proper milieu with sufficient oxygen and nutrient permeation to support cell population and their distribution appropriately …”

Section: Introductionmentioning

confidence: 99%

Electrospun electroactive nanofibers of gelatin‐oligoaniline/Poly (vinyl alcohol) templates for architecting of cardiac tissue with on‐demand drug release

Shojaie

Rostamian

Samadi

et al. 2019

Polymers for Advanced Techs

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In this study, grafted gelatin with oligoaniline (GelOA) was synthesized and then mixed with Poly (vinyl alcohol) (PVA). Several scaffolds with different ratio of PVA/GelOA were electrospun to fabricate electroactive scaffolds. GelOA was characterized using Fourier‐transform infrared spectroscopy (FTIR); moreover, nanofiber properties were evaluated by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and scanning electron microscope (SEM) analyses. Nanofibers diameter was decreased with aniline oligomer increment form 300 to 150 nm because of the hydrophobic nature of the aniline oligomer. Aniline oligomer electroactivity was studied using cyclic voltammetry, which exhibited two redox peaks at 0.4 and 0.6. Moreover, aniline oligomer enhancement resulted in melting point increasing from 220°C to 230°C because of the crystallinity increment. To assess the biocompatibility of nanofibers, cell viability and cell adhesion were tracked using mesenchymal stem cell (MSCs). It was revealed that the presence of aniline oligomer leads to enhancing the conductivity, thermal properties and lowering the degradation rate and drug release. Among of different scaffolds, sample with high content of GelOA shows better behavior in physical and biological properties. Accumulative drug releases under applied electrical field at 40 minutes showed that the drug release for stimulated condition is about 33% more than the unapplied electrical field one.

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“…As a result, Sn derivatives generate PLAs with sufficiently high‐molecular weight. Nevertheless, tin has serious environmental threats; hence, a substitute metal had to be considered . Single‐site active metal alkoxide catalyst precursors were applied to precede ring opening polymerization of PLA .…”

Section: Introductionmentioning

confidence: 99%

Facile catalytic ring opening polymerization of lactic acid: Comparing the performance of Fe and Zn metal species

Yaghobinia

Ahmadi

Abdouss

2018

Vinyl Additive Technology

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As a bio-compatible/degradable polymer, poly(lactic acid) (PLA) has been widely noticed in tissue engineering and medical applications. Proper catalytic ringopening polymerization of lactic acid is pertinent to development of active metal species capable of producing high-molecular-weight polymers. In this work, ligand catalyst (2,4-di-tertio-butyl-6-{[(2-di-methyl-amino ethyl) methyl amino] methyl} phenol) was synthesized and then attached to Fe-based and Zn-based metal substitutes, and performance of metal species toward ring opening polymerization of lactic acid has been investigated. Regulation of reaction condition at 180 C for 36 h with Zn-based catalyst allowed for late-stage production of a high-molecular-weight PLA, while Fe-based facilitated polymerization at early stages leading to PLAs with comparatively twofold higher molecular weight at lower time, monomer-to-initiator ratio, and temperature (at 170 C). A ratio of monomer to initiator of 5000 with Fe catalyst resulted in the highest molecular weight. Thus, polymerization has been facilitated by the use of Fe-based catalyst. For this class of catalyst with Fe substitute, the product was characterized by means of 1 H-NMR, Fourier transform infrared spectroscopy, and differential scanning calorimetry analyses. J. VINYL ADDIT. TECHNOL., 25:215-224, 2019.

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Tissue engineering; strategies, tissues, and biomaterials

Cited by 154 publications

References 220 publications

Proteins and Peptides as Important Modifiers of the Polymer Scaffolds for Tissue Engineering Applications—A Review

Proteins and Peptides as Important Modifiers of the Polymer Scaffolds for Tissue Engineering Applications—A Review

Electrospun electroactive nanofibers of gelatin‐oligoaniline/Poly (vinyl alcohol) templates for architecting of cardiac tissue with on‐demand drug release

Facile catalytic ring opening polymerization of lactic acid: Comparing the performance of Fe and Zn metal species

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