Timing of the Availability and Administration of Influenza Vaccine Through the Vaccines for Children Program

Bhatt, Praful; Block, Stan L.; Toback, Seth; Ambrose, Christopher S.

doi:10.1097/inf.0b013e3181efff54

Cited by 25 publications

(17 citation statements)

References 10 publications

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“…VFC-eligible children who visit the practice before supplies arrive often leave unvaccinated and may not return later in the season to be vaccinated. Although the difference in delivery dates is decreasing, studies have reported that VFC vaccines arrive 2-4 weeks later than commercial supplies, which results in lower two dose compliance rates [32, 33]. Intervention practices rated early delivery of vaccine supplies as the most effective strategy available to them during the intervention.…”

Section: Discussionmentioning

confidence: 99%

Cluster randomized trial of a toolkit and early vaccine delivery to improve childhood influenza vaccination rates in primary care

Zimmerman¹,

Nowalk²,

Lin³

et al. 2014

Vaccine

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Purpose To increase childhood influenza vaccination rates using a toolkit and early vaccine delivery in a randomized cluster trial. Methods Twenty primary care practices treating children (range for n=536-8,183) were randomly assigned to Intervention and Control arms to test the effectiveness of an evidence-based practice improvement toolkit (4 Pillars Toolkit) and early vaccine supplies for use among disadvantaged children on influenza vaccination rates among children 6 months-18 years. Follow-up staff meetings and surveys were used to assess use and acceptability of the intervention strategies in the Intervention arm. Rates for the 2010-2011 and 2011-2012 influenza seasons were compared. Two-level generalized linear mixed modeling was used to evaluate outcomes. Results Overall increases in influenza vaccination rates were significantly greater in the Intervention arm (7.9 percentage points) compared with the Control arm (4.4 percentage points; P<0.034). These rate changes represent 4522 additional doses in the Intervention arm vs. 1,390 additional doses in the Control arm. This effect of the intervention was observed despite the fact that rates increased significantly in both arms - 8/10 Intervention (P<0.001) and 7/10 Control sites (P-values 0.04 to <0.001). Rates in two Intervention sites with pre-intervention vaccination rates >58% did not significantly increase. In regression analyses, a child's likelihood of being vaccinated was significantly higher with: younger age, white race (Odds ratio [OR]=1.29; 95% confidence interval [CI]=1.23-1.34), having commercial insurance (OR=1.30; 95%CI=1.25-1.35), higher pre-intervention practice vaccination rate (OR=1.25; 95%CI=1.16-1.34), and being in the Intervention arm (OR=1.23; 95%CI=1.01-1.50). Early delivery of influenza vaccine was rated by Intervention practices as an effective strategy for raising rates. Conclusions Implementation of a multi-strategy toolkit and early vaccine supplies can significantly improve influenza vaccination rates among children in primary care practices but the effect may be less pronounced in practices with moderate to high existing vaccination rates.

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Section: Discussionmentioning

confidence: 99%

Cluster randomized trial of a toolkit and early vaccine delivery to improve childhood influenza vaccination rates in primary care

Zimmerman¹,

Nowalk²,

Lin³

et al. 2014

Vaccine

View full text Add to dashboard Cite

show abstract

“…Historically, the majority of influenza vaccinations have been administered between October and December [8][9][10][11]. In 2007, the ACIP recommended initiation of seasonal influenza vaccination as soon as vaccines became available [12].…”

Section: Introductionmentioning

confidence: 99%

Seasonal influenza vaccination trends from 2007–2011 in privately insured children and adults in the United States

Antonova¹,

Ambrose

Kern

et al. 2014

Vaccine

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Annual influenza vaccination claims for privately-insured children and adults increased and shifted earlier from 2007 through 2009-2011. During the 2011-2012 influenza season, 25.4% of children aged 6 months-17 years and 12.3% of adults aged 18-64 years were vaccinated. Increasing influenza vaccination should remain a priority, and alternative venues for seasonal influenza vaccination should be considered in order to meet the Healthy People 2020 goal of 80% to 90% coverage among children.

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“…12 Although reminder-recall systems that notify families that their child needs a vaccine are widely recommended, 13,14 traditional strategies implemented via mail or telephone have had limited to no efficacy in urban, low-income, and minority populations [15][16][17] who are also at high risk for undervaccination. 18,19 We recently demonstrated the effectiveness of using text message reminders for first influenza vaccine doses in this population. 20 However, the impact of such reminders on return for a second needed dose is unknown.…”

Section: What This Study Addsmentioning

confidence: 99%

Text Message Reminders for Second Dose of Influenza Vaccine: A Randomized Controlled Trial

et al. 2015

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To determine whether provision of vaccine-health-literacy-promoting information in text message vaccine reminders improves receipt and timeliness of the second dose of influenza vaccine within a season for children in need of 2 doses.METHODS: During the 2012-2013 season, families of eligible 6-month through 8-year-old children were recruited at the time of their first influenza vaccination from 3 community clinics in New York City. Children (n = 660) were randomly assigned to "educational" text message, "conventional" text message, and "written reminder-only" arms. At enrollment, all arms received a written reminder with next dose due date. Conventional messages included second dose due date and clinic walk-in hours. Educational messages added information regarding the need for a timely second dose. Receipt of second dose by April 30 was assessed by using x 2 tests. Timeliness was assessed by receipt of second dose by 2 weeks after due date (day 42) using x 2 and over time using a Kaplan-Meier analysis.RESULTS: Most families were Latino and publicly insured with no significant between-arm differences between groups. Children in the educational arm were more likely to receive a second dose by April 30 (72.7%) versus conventional (66.7%) versus written reminder-only arm (57.1%; P = .003). They also had more timely receipt by day 42 (P , .001) and over time (P , .001).CONCLUSIONS: In this low-income, urban, minority population, embedding health literacy information improved the effectiveness of text message reminders in promoting timely delivery of a second dose of influenza vaccine, compared with conventional text messages and written reminder only. WHAT'S KNOWN ON THIS SUBJECT:Influenza vaccine coverage is low, and young children in need of 2 doses in a given season are at particular risk, with less than half receiving both doses. Text message vaccine reminders increase receipt of first dose of influenza vaccine. WHAT THIS STUDY ADDS:Little is known about what types of text message reminders are most effective, including embedding educational information. We demonstrate that text message reminders increase timely receipt of the second dose of influenza vaccine and embedding health literacy information improves effectiveness.

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Timing of the Availability and Administration of Influenza Vaccine Through the Vaccines for Children Program

Cited by 25 publications

References 10 publications

Cluster randomized trial of a toolkit and early vaccine delivery to improve childhood influenza vaccination rates in primary care

Cluster randomized trial of a toolkit and early vaccine delivery to improve childhood influenza vaccination rates in primary care

Seasonal influenza vaccination trends from 2007–2011 in privately insured children and adults in the United States

Text Message Reminders for Second Dose of Influenza Vaccine: A Randomized Controlled Trial

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