Timing of Spheno-Occipital Synchondrosis Closure in Cleft Lip and Palate Patients in Iranian Population

Abstract

This study aimed to evaluate the chronological age range associated with each stage of spheno-occipital synchondrosis (SOS) fusion in patients with cleft lip and palate compared to the noncleft group, using cone-beam computed tomography (CBCT) images. Design: In this study, the degree of SOS fusion was assessed using a 4-stage scoring system on CBCT images of 190 individuals (92 patients with cleft lip and palate, 98 noncleft individuals). A χ2 test was performed to assess the correlation between age and fusion stage. The independent sample t tests were used to evaluate the differences in the mean values of the samples of each group and each sex, as well as the mean value of each stage ( P < .05). Results The results showed that there was no significant difference in the timing of the SOS fusion stages between the patients with cleft palate and the noncleft group. Although the fusion process of SOS begins about one year earlier in females, the complete ossification occurs at the mean age of 18.5 for both sexes in the experimental group and the mean age of 19.0 in the noncleft group. Conclusions The present study found no differences in the fusion stages of the spheno-occipital synchondrosis between patients with cleft lip and palate and healthy individuals.

Skeletal Age Status Determination Using the Spheno‐Occipital Synchondrosis Closure in a Cameroonian Population: An Analytical Study

“…Our results are similar to Bassed and colleagues who had no statistical difference between males and females after the age of 16 [3]. Other studies have shown a difference between males and females [8, 16, 18–22] and they evoked a possible link between hormones and early SOS closure.…”

“…Other studies have shown a difference between males and females [8,16,[18][19][20][21][22] and they evoked a possible link between hormones and early SOS closure.…”

“…Biological studies are interested in SOS behavior because it occurs together with childhood and adolescent growth. It is one of the few bone structures that can be used to determine age during this stage of life [16].…”

Skeletal Age Status Determination Using the Spheno‐Occipital Synchondrosis Closure in a Cameroonian Population: An Analytical Study

“…Our results are similar to Bassed and colleagues who had no statistical difference between males and females after the age of 16 [3]. Other studies have shown a difference between males and females [8, 16, 18–22] and they evoked a possible link between hormones and early SOS closure.…”

“…Other studies have shown a difference between males and females [8,16,[18][19][20][21][22] and they evoked a possible link between hormones and early SOS closure.…”

“…Biological studies are interested in SOS behavior because it occurs together with childhood and adolescent growth. It is one of the few bone structures that can be used to determine age during this stage of life [16].…”

Skeletal Age Status Determination Using the Spheno‐Occipital Synchondrosis Closure in a Cameroonian Population: An Analytical Study

“…Our results are similar to Bassed and colleagues who had no statistical difference between males and females after the age of 16 [3]. Other studies have shown a difference between males and females [8, 16, 18–22] and they evoked a possible link between hormones and early SOS closure.…”

“…Other studies have shown a difference between males and females [8,16,[18][19][20][21][22] and they evoked a possible link between hormones and early SOS closure.…”

“…Biological studies are interested in SOS behavior because it occurs together with childhood and adolescent growth. It is one of the few bone structures that can be used to determine age during this stage of life [16].…”

Skeletal Age Status Determination Using the Spheno‐Occipital Synchondrosis Closure in a Cameroonian Population: An Analytical Study

“…Our results are similar to Bassed and colleagues who had no statistical difference between males and females after the age of 16 [3]. Other studies have shown a difference between males and females [8, 16, 18–22] and they evoked a possible link between hormones and early SOS closure.…”

“…Other studies have shown a difference between males and females [8,16,[18][19][20][21][22] and they evoked a possible link between hormones and early SOS closure.…”

“…Biological studies are interested in SOS behavior because it occurs together with childhood and adolescent growth. It is one of the few bone structures that can be used to determine age during this stage of life [16].…”