Time-related improvement of survival in resectable gastric cancer: the role of Japanese-style gastrectomy with D2 lymphadenectomy and adjuvant chemotherapy

Abstract

The global prognosis and that of some stages have improved in recent years with case RGC patients treated with surgery and adjuvant chemotherapy.

Survival outcomes after D1 and D2 lymphadenectomy with R0 resection in stage II–III gastric cancer: Longitudinal follow-up in a single center

“…Two studies from the Memorial Sloan-Kettering Cancer Center demonstrated survival differences for T1-T3 tumors in favor of Japanese patients and improved survival after matching by T stage and location in Korean patients compared to the US patients (26,27). However, as observed in our recent and previous study, it is promising that the inconsistency of the surgical approach between Japan and the Western groups, particularly in terms of the extent of nodal resection, is being eliminated, such that better outcomes in the D2 groups with an operative mortality rate of less than 4% and an increased rate of cases having at least 15 lymph nodes removed is being reported both in randomized control trials and observational studies by surgical teams who had acquired experience through the years spent in Western countries (11,(28)(29)(30)(31)(32)(33)(34)(35)(36). The results of the Dutch and UK trials have been criticized for the unacceptably high mortality and poor survival rates, as well as the non-compliance of surgeons (24).…”

Role of Hydro-Dissection Facilitated Monopolar Cauterization Dissection Technique on Separation of the Greater Omentum From the Superior Layer of the Transverse Mesocolon During D2 Radical Gastrectomy

“…The overall survival rates of the present study after D2 radical gastrectomy are similar to other studies. 6,21,22 Experience of the surgeon is another important factor for a safe and adequate D2 radical gastrectomy. The high number of removed lymph nodes (Table 1) is a good indicator for the experience and practice of the surgeons who took part in the present study.…”

Prediction of Liver Metastases After Gastric Cancer Resection with the Use of Learning Vector Quantization Neural Networks

“…The surgical procedure was performed according to standards described elsewhere [15][16][17]. Resected specimens were examined according to standard pathohistological procedures and classified according to criteria described by the Japanese Research Society for Gastric Cancer [15][16][17]. The anatomical location, diameter of the tumor, lymphocyte invasion, vascular invasion, lymphangial invasion, extranodal invasion, and perineural invasion were all noted.…”

“…The strategy was to achieve R0 resection (assuring 4-5-cm tumor-free safety margins in intestinal type; 8-10-cm tumor-free safety margins in diffuse type according to Lauren) accompanied by D2 lymphadenectomy. The surgical procedure was performed according to standards described elsewhere [15][16][17]. Resected specimens were examined according to standard pathohistological procedures and classified according to criteria described by the Japanese Research Society for Gastric Cancer [15][16][17].…”