volume 94, issue 4, P429-433 2019
DOI: 10.1590/abd1806-4841.20198022
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Abstract: Background: Behçet disease is a prototypical systemic autoimmune disease, caused by a complex interplay between environmental and genetic factors. The transmembrane immunoglobulin and mucin domain-3 (TIM-3) is a distinct member of the TIM family that is preferentially expressed on Th1 cells and plays a role in Th1-mediated autoimmune or inflammatory diseases, such as Behçet disease. oBjective: The aim of this study was to test the potential association between TIM-3 gene polymorphisms and Behçet disease. Metho…

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