1998
DOI: 10.1136/bmj.317.7160.703
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Abstract: Objective: To determine whether tight control of blood pressure prevents macrovascular and microvascular complications in patients with type 2 diabetes. Design: Randomised controlled trial comparing tight control of blood pressure aiming at a blood pressure of < 150/85 mm Hg (with the use of an angiotensin converting enzyme inhibitor captopril or a blocker atenolol as main treatment) with less tight control aiming at a blood pressure of < 180/105 mm Hg. Setting: 20 hospital based clinics in England, Scotland, … Show more

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Cited by 5,587 publications
(235 citation statements)
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“…Nos pacientes com DM2, cerca de 40% já se encontram hipertensos por ocasião do diagnóstico de diabetes. Evidências epidemiológicas indicam que pacientes com DM2 apresentam risco aumentado para doenças cardiovasculares, onde a dislipidemia exerce o papel mais importante [5][6][7].…”
Section: Introductionunclassified
“…Nos pacientes com DM2, cerca de 40% já se encontram hipertensos por ocasião do diagnóstico de diabetes. Evidências epidemiológicas indicam que pacientes com DM2 apresentam risco aumentado para doenças cardiovasculares, onde a dislipidemia exerce o papel mais importante [5][6][7].…”
Section: Introductionunclassified
“…It is well documented that DM is associated with a variety of small and large blood vessel disease, which plays a role in developing a myriad of body organ pathologies, including nephropathy, retinopathy, CVD and elevated BP. In a study on HTN and type 2 DM, tight control of BP significantly reduced risks of deaths and vasculopathic complications related to diabetes [43]. To this end, we may learn from this research through the significant correlation between SBP and RPG that IHPG can be risk for developing pre-HTN/HTN.…”
Section: Discussionmentioning
confidence: 97%
“…[32][33][34] There were also significant correspondences between scores derived from the ActiGraph accelerometer and VO 2 treadmill testing (r = 0.82-0.87) 34 and doubly labeled water measurements (r = 0.39-0.54) 35 …”
Section: Methodsmentioning
confidence: 92%