1997
DOI: 10.1001/archderm.133.10.1313
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'Tiger tail' pattern on polarized hair microscopic examination is found in healthy infants

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Cited by 7 publications
(5 citation statements)
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“…Initially, collodion baby was believed to occur only in patients with TTD without XPD mutation, but Marinoni et al 102 copy. 105 Within the past few years, it has been shown that "tiger-tail" pattern on polarized hair microscopic examination also may be found in healthy infants, and therefore amino acid analysis that quantitates sulfur, specifically cyst(e)ine levels, remains the definitive test for TTD 110,111 (Table III). In this regard Garcia-Hernandez and Moreno-Giménez 112 have documented alternating dark and white zones within the hair shaft of a young patient who scratched his scalp intensely.…”
Section: Ttd Syndromes: Delineation and Spectrum Of Expressionmentioning
confidence: 99%
“…Initially, collodion baby was believed to occur only in patients with TTD without XPD mutation, but Marinoni et al 102 copy. 105 Within the past few years, it has been shown that "tiger-tail" pattern on polarized hair microscopic examination also may be found in healthy infants, and therefore amino acid analysis that quantitates sulfur, specifically cyst(e)ine levels, remains the definitive test for TTD 110,111 (Table III). In this regard Garcia-Hernandez and Moreno-Giménez 112 have documented alternating dark and white zones within the hair shaft of a young patient who scratched his scalp intensely.…”
Section: Ttd Syndromes: Delineation and Spectrum Of Expressionmentioning
confidence: 99%
“…There was one instance of pili torti and one of carbamoyl phosphate synthetase deficiency. A third category of four samples (cases [11][12][13][14] had abnormalities of hair microscopy in all three of the three categories of cuticle, shaft and distal end in all but one subject, who had a relatively spared cuticle. In all samples there were partial or complete tiger-tail changes on polarized light microscopy but the amino acids were normal.…”
Section: Resultsmentioning
confidence: 95%
“…Alternating light and dark bands are also seen using cross-polarizing filters in pseudo-pili annulati, 10 loose anagen syndrome and the hair of some healthy infants. 11,12 Not all of these have the same appearance, with sinuous cortical fibres. These variations mean that tiger-tail changes are sensitive but not wholly specific to TTD.…”
Section: Discussionmentioning
confidence: 99%
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“…However, hair examination from a 21-week gestation, aborted fetus showed the alternating light and dark banding pattern under the polarized light microscope [38]. Within the last few years, it has been shown that the tiger tail pattern on polarized hair microscopic examination may also be found in healthy infants, and therefore amino acid analysis quantitating sulfur – specifically cyst(e)ine) levels – remains the definitive test for TTD [39, 40]. In this regard, Garcia-Hernandez et al [41] have documented alternating dark and white zones within the hair shaft of a young patient who scratched his scalp intensely.…”
Section: Hair Shaft Alterations In Ectodermal Dysplasiasmentioning
confidence: 99%