2001
DOI: 10.1590/s0004-282x2001000500014 View full text |Buy / Rent full text
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Abstract: We evaluated 44 patients with tics and Tourettes syndrome (TS) emphasising the age of onset of symptoms, sex, classification and localization of tics, associated symptoms and signs and comorbidities. Thirtythree patients (75.2%) had TS defined criteria whereas 10 (22.7%) had chronic motor and/or vocal tics. Simple motor tics were found in 43 cases (97.7%), mainly affecting the eyes (43.2%), mouth (43.2%), face (34.1%). Simple vocal tics occurred in 33 (75%). Coprolalia was found in just 6 cases (13.6%) and cop… Show more

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“…In 16 uncontrolled studies in specialist centers examining mood changes among 5409 GTS patients, depressive symptomatology, dysthymia, mood swings and/ or MDD, or depressive illness was found in 13-76%. The main diagnosis was MDD [23,27,[31][32][33][34][35][36][37][38][39][40][41][42][43][44].…”
Section: Comorbidity and Psychopathologymentioning
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“…In 16 uncontrolled studies in specialist centers examining mood changes among 5409 GTS patients, depressive symptomatology, dysthymia, mood swings and/ or MDD, or depressive illness was found in 13-76%. The main diagnosis was MDD [23,27,[31][32][33][34][35][36][37][38][39][40][41][42][43][44].…”
Section: Comorbidity and Psychopathologymentioning
“…In a recent study, coprolalia was suggested to be a potential risk factor for malignant evolution of GTS1 and, evidently, has an important social and professional impact. The frequency of this symptom is estimated to range from 8% to 26% depending on the study population 2, 3. The pathophysiology of coprolalia is poorly understood.…”
mentioning
“…The estimated prevalence of the disease ranges from 1 to 10 per 1000 children and adolescents, being associated with various comorbidities such as attention deficit and obsessive-compulsive disorders 1,2 . These comorbidities have been reported in various series of Brazilian patients in the literature [3][4][5] . It is believed nowadays that Ts has significant genetic determinant, and several candidate genes have been described.…”
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